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New on bioRxiv! 🧠🧬
Our work uncovers how modularity in the DCC-ECD shapes axon guidance and neuronal migration.Using mouse lines with mutations in Netrin-1 and Draxin binding sites, we show how distinct DCC modules drive precise circuit assembly
#Neuroscience #AxonGuidance #DCC #Netrin1 #Draxin

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Renal Arteriogenesis by
FoxD1+ stromal progenitor-derived #Netrin1

1) Endothelial #BranchingMorphogenesis
2) #MuralCell vessel coverage
3) Timely differentiation of Six2+ nephron progenitors

@ondinecleaver.bsky.social Development 2023
1/5🧵
journals.biologists.com/dev/article/...

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