Can diet + drugs force cancer cells to grow up instead of multiplying? 🧬🍽️ New research in mice finds restricting key amino acids with a polyamine-blocking drug triggers aggressive neuroblastoma cells to mature. www.news-medical.net/news/2026040... #Neuroblastoma #Cancer @nejm.org

#PBC Must Read: Imaging of High-Risk #Neuroblastoma: Recommendations From SIOPEN Radiology and Nuclear #Medicine Specialty Committees
Read more: onlinelibrary.wiley.com/doi/10.1002/...

Challenges and overcoming strategies in CAR-T cell therapy for pediatric neuroblastoma.

#pediatric #Meded #Medx #Science #CART #therapy #Neuroblastoma

Oral solid lipid nanoparticles of etoposide enable metronomic-like therapy with reduced toxicity in MYCN-amplified neuroblastoma Therapeutic regimens for pediatric malignancies such as neuroblastoma remain complex and are often associated with severe systemic toxicity. The devel…

What if oral etoposide could work better in a neuroblastoma with less toxicity?

New paper: oral solid lipid nanoparticles improved bioavailability, and slowed tumor growth.
The team used HypoxyLab + OxyLite to create and verify stable hypoxia in vitro.

#Neuroblastoma #Hypoxia #CancerResearch

early morning setup with sydney striders getting everything ready for run2cure 💛🏃‍♂️

every step today is for raising awareness and supporting kids with neuroblastoma

#sydneystriders #morningvibe #charityrun #neuroblastoma #run2cure #communityrun #10krun

Urgência no acesso a tratamento para neuroblastoma pelo SUS é debatida no Senado

#AtualizaçõesLegislativas #acessoaoSUS #neuroblastoma #tratamentocâncerinfantil Urgência no acesso a tratamento para neuroblastoma pelo SUS é debatida no SenadoO neuroblastoma é um câncer comum em crianças pequenas, originando-se nas células nervosas. O acesso a tratamentos essenciais, como o betadi

#Agenda | #CPMIdoINSS se reúne para analisar requerimentos. Subcomissão realiza audiência sobre #neuroblastoma. Comissão para Reforma do #CódigoCivil debate Direito de Família e Direito das Sucessões.

Effect of MYCN Amplification on Tumor Response and Recurrence in Patients With Stage IV Neuroblastoma | JCO Precision Oncology PURPOSEMYCN amplification (MYCN-A) is an important prognostic marker in neuroblastoma. However, the impact of MYCN-A in patients with metastasized high-risk neuroblastoma during the course of disease ...

A pesar de alcanzar una remisión completa más rápido, los pacientes con amplificación MYCN tienen mayor probabilidad de recurrencia comparados con los que no tienen esta amplificación #MYCN #Neuroblastoma ascopubs.org/doi/full/10....

Integrating next-generation sequencing into the routine neuroblastoma workflow identifies actionable genomic alterations and reduces low-yield karyotype testing - Virchows Archiv Neuroblastoma (NB) is a genetically complex entity. Alterations at both the gene and chromosomal levels have been identified in NB, some with prognostic and therapeutic implications. More recently, AL...

We hope you find our recent contribution to #PediPath useful: doi.org/10.1007/s004...
#Neuroblastoma #PediatricCancer #MolecularPathology
@UMiamiPathology
pubmed.ncbi.nlm.nih.gov/41840189/

"New at JCAT-radiology
'Association of Image-Defined Risk Factors With 18F-FDG PET/CT Metabolic Metrics in Neuroblastoma: Location-Specific Correlations and Comparative Prognostic Significance'
Jan/Feb 26 tinyurl.com/43jxcnfj Au: Haoru Wang et al.
#radiology #neuroblastoma #FDGPET

"New at JCAT-radiology
'Association of Image-Defined Risk Factors With 18F-FDG PET/CT Metabolic Metrics in Neuroblastoma: Location-Specific Correlations and Comparative Prognostic Significance'
Jan/Feb 26 tinyurl.com/43jxcnfj Au: Haoru Wang et al.
#radiology #neuroblastoma #FDGPET

Table outlines HMH characteristics among SDOH study participants, N=417. Categories include 'Any HMH@1', 'HMH severity@2' (Mild: 49, Severe: 78), and 'HMH domain@3' (Food insecurity: 70, Housing insecurity: 69, Utility insecurity: 43, Transportation insecurity: 32).

Parent-reported #SDOH data collection during a COG high-risk #Neuroblastoma trial was feasible, with nearly 90% completion and one-third of families reporting household material hardship.

ja.ma/4l8tVnU

#PBC Must Read: Improved Outcomes for Older Children, Adolescents, and Young Adults With #Neuroblastoma in the Post #Immunotherapy Era: An Updated Report From the International Neuroblastoma Risk Group. #AYA #RebeccaJDeyell #Pediatric #Oncology #Hematology #PedsHemeOnc buff.ly/AAOpjtb

🎗️ 15th of February is #InternationalChildhoodCancerDay.

At #Mac4Me, our ultimate goal is to improve treatment options for metastatic #Neuroblastoma. We research:

🔹 3D printing miniature brain models to stop tumor survival.

🔹 Chips that mimic blood flow to block cancer from spreading.

Competitors rejected these projects. We delivered. 🧬

We achieved successful knockouts in a notoriously difficult #Neuroblastoma model.

How? #CellEDIT bypasses barriers with Direct, Vector-Free Delivery. ✅ Precise Stoichiometry ✅ Gentle Handling

#GeneEditing #CRISPR #Biotech #Oncology #Cytosurge

Brazilian consensus update: autologous HSCT remains central to consolidation in high-risk #neuroblastoma. Single BuMel is recommended nationally, w/ post-transplant radiotherapy, isotretinoin, and anti-GD2 improving survival, while toxicity surveillance is essential.
doi.org/10.46765/267...
#MedSky

Black Country girl with neuroblastoma sets 8,000 birthday card target Amelia, who is on palliative care, hopes to break the UK record for most birthday cards received.

go for it guys:
#Amelia8000
#Amelia
#BlackCountry
girl with #neuroblastoma sets 8,000 birthday card target - BBC News
www.bbc.co.uk/news/article...

Rho GTPases signaling mediates aggressiveness and differentiation in neuroblastoma tumors

Check out our new research article describing the role of the #RhoGTPase family of signalling molecules in #neuroblastoma tumours.

rdcu.be/eZUzA

Today we’re at the SIOPEN Translational Research Meeting 2026 in Berlin 🧬. Jointly organized with the pediatric oncology team at Charité – Universitätsmedizin Berlin.
Looking forward to great science and discussions on translating research into better outcomes for children with #Neuroblastoma.

HLA-Shuttle: A system for enhancing antigen presentation in immunologically cold tumors HLA-Shuttle enhances production of HLA class I molecules in neuroblastoma, leading to the discovery of tumor-associated antigens.

Researchers Nikolaos Sgourakis and John Maris from team NexTGen (co-funded by @themarkfdn.bsky.social) created a discovery system to identify new antigens in neuroblastoma.

📖 Read the Science Advances paper: doi.org/10.1126/scia...

#CancerResearch #neuroblastoma #CancerGrandChallenges

This review explores #MYCN-driven #oncogenesis in #neuroblastoma, outlines emerging therapies, and highlights that dual targeting of MYCN and the #MDM2 #oncogene is a promising strategy for high-risk neuroblastoma and other #cancers. @uh.edu

#OpenAccess: doi.org/10.1016/j.ge...

I had 20% chance of surviving cancer as a child & now have a miracle daughter A WOMAN warned she was unlikely to survive childhood cancer has defied the odds with her own miracle daughter. Demie Risby was diagnosed with neuroblastoma at the age of six and told she had a less…

From <20% chance to thriving and a mum with her own miracle! Demie Risby beat advanced #neuroblastoma as a kid and now nurses others while inspiring countless families! #TCSC #SurvivorStory #Hope #CancerSurvivor www.thesun.co.uk/health/37740... 

Recent #neuroblastoma bulk #mRNA dataset added to R2platform

Gene expression profile of Kelly and SH-SY5Y cells after treatment with retinoic acid

R2 open online nocode data science platform for biomedical researchers

r2platform.com

3.000+ citations in PubMed

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This year, we’ve added OpenScPCA annotations to downloads for two ScPCA projects:

-SCPCP000004 #Neuroblastoma
-SCPCP000015 #EwingSarcoma

Learn more about OpenScPCA! openscpca.readthedocs.io/en/latest/

Tunbridge Wells cancer survivor urges people to 'enjoy every day' Kent mother Demie Risby is now a paediatric nurse at Great Ormond Street Hospital.

From 20% chance of survival to pediatric nurse and mum: Demie Risby’s rare childhood cancer story is a powerful reminder to grab the good days and never stop hoping. Read her story: www.bbc.co.uk/news/article... #CancerSurvivor #Neuroblastoma #Hope #TCSC

#neuroblastoma singlecell, #cell line #Atlas of 13 widely used #NRBL models

r2platform.com

A dedicated public resource, ready for immediate exploration by biomedical researchers

A Novel Prognostic Metric Resolves the MYCN enigma in Silico and Points to a Biosynthetic Regulatory Shift Driven by MYCN Amplification in Neuroblastoma Neuroblastoma (NB) is the most common extra-cranial solid tumour in children. Although MYCN amplification is typically indicative of a poor prognosis, the expression level of MYCN has a non-monotonic ...

🔹 Favourable outcomes in MYCN-amplified tumours require very high biosynthesis and ATM signalling — rarely achievable biologically.

Read here: biorxiv.org/content/10.1...
#neuroblastoma #modelling #cancerresearch

#ADRENAMEDULLA26 #Pheochromocytoma #CatecholamineSynthesis #Neuroblastoma #MultipleEndocrineNeoplasia #PKU #Phenylketonuria #VitaminC #AdrenalTumors #MedicalEducation #Endocrinology #HormonalPathways #GeneticDisorders #MedicalInfographic #PH #TyrosineHydroxylase #Dopamine #AdrenalGland #HormonalDisorders #Genetics

#ADRENAMEDULLA26
#Pheochromocytoma #CatecholamineSynthesis #Neuroblastoma #MultipleEndocrineNeoplasia #PKU #Phenylketonuria #VitaminC #AdrenalTumors #MedicalEducation #Endocrinology #HormonalPathways #GeneticDisorders #MedicalInfographic #PH #TyrosineHydroxylase #Dopamine #AdrenalGland