#Medsky🧪 #IDsky #microsky #microsky #publichealth Epitope-focused discovery strategies have successfully identified rare, potent antibodies capable of neutralizing highly evolved #SARSCoV2 #Omicronvariants by targeting conserved or novel sites of vulnerability.
This study highlights
-Following 💉, the study found GC- B cells that could bind to both the ancestral strain & the #Omicronvariants BA.1, BQ.1.1 & XBB.1.5, showing a broad response.
- An examination of the broadly mAb-52 revealed that its wide-ranging effectiveness was not part of the original, unmutated sequence.
#Medsky🧪 #IDsky #immunosky #publichealth @nature.com In conclusion, the study showed that a boost with the ancestral strain in vaccine IH Ad5-nCoV was associated with a lower incidence of symptomatic #COVID caused by #Omicronvariants, in adults predominantly with #hybridimmunity against #SARSCoV2.
