Universal orthologs infer deep phylogenies and improve genome quality assessments. #Orthologs #Phylogenies #GenomeQualityAssessment #Bioinformatics #BMCbiology 🧬 🖥️
bmcbiol.biomedcentral.com/articles/10....

Single-cell analysis of a salmonid immune system (brown trout Salmo trutta) reveals evolutionary divergence and hatchery-induced transcriptional reprogramming Vertebrate immune systems exhibit striking evolutionary diversity, yet our understanding remains biased toward mammalian models. Here, we generate a single-cell atlas of immune cells from the ecologic...

the #salmonid #brown #trout features #hatchery-induced gene expression in #immune cells. This may explain some issues in #stocking programs. Also: #orthologs with contrasting expression patterns, indicating functional divergence! Also: novel #markers for immune cell subtypes for qPCR!

#BUSCO v2 with #OrthoDB v9 #orthologs ready for BETA-TESTING 14 #metazoa, 2 #protist, and 10 #fungi lineages, PM/email me if interested