What is the optimal teicoplanin target for E. faecium bacteraemia? Yamaguchi et al. found a freeAUC24/MICEtest of ≥462 reduces treatment failure:
doi.org/10.1093/jaca...
#JACAMRNews #IDSky #AMR #PKPD

Pharmacokineticist, PK/PD Modelling & Simulation Pharmacokineticist, PK/PD Modelling & Simulation

Opportunity in pharmacokinetics & PK/PD modelling at Lundbeck (Copenhagen Denmark) ref: 6758 | closing: 16-Sep-2025 #DMPK #PK #PKPD #chemsky 🧪
jobs.lundbeck/job/Copenhag...

The first #FlashTalk session of the #LED3Symposium gave us insights into early #PKPD modelling for predicting the outcome of clinical studies for #tuberculosis treatment (Asina Gijasi) and into self-encoded libraries for affinity-selection MS of macrocyclic compounds (cycloSELs, Miguel Mata).

#IDSky #PKPD #ganciclovir #CMV

The pharmacokinetics of antibiotics in patients with obesity: a systematic review and consensus guidelines for dose adjustments Obesity can cause physiological changes resulting in antibiotic pharmacokinetic alterations and suboptimal drug exposures. This systematic review aime…

Happy to share this systematic review on antibiotic dosing in obesity! Thank you all the co-authors, it was great working together on this! #IDSky #PKPD #ESCMID

www.sciencedirect.com/science/arti...

💊 Suivi thérapeutique : antiviraux, antifongiques, antirétroviraux… on fait le point !
La #RICAI2024 explore l’intérêt du dosage au-delà des antibiotiques avec des cas concrets.

🎥 À voir ici ➡️ https://shorturl.at/Wf7ro
#Pharmacologie #PKPD #Infectiologie

Our #PKPD workshop (22 - 23 May) covers data analysis, measurements, and study design. Join us at 1 Wimpole Street, the home of the Royal Society of Medicine. ➡️ Register Today!
🔗 my.bps.ac.uk/events/detai...

We’re heading to #PAGE2025 in Thessaloniki next month! 🎉 Mark Davies & Lea Sta are looking forward to sharing how our expertise in #PKPD, #MIDD & model-based strategies helps de-risk and optimise #drugdevelopment. Planning to attend? Drop us a message – we’d love to meet. #PYC

We’re heading to #ASCPT2025 in Washington DC, 28-30th May! 🌎 As specialists in #PKPD modelling, #QSP and biostatistics, we help pharma and biotech teams make smarter, faster development decisions. Come chat to our team to learn more - reach out to book a meeting! #PYC

Build your skills in #pharmacokinetics and #pharmacodynamics at our upcoming #PKPD workshop, taking place 22–23 May in London. 💊Perfect for researchers, clinicians, and anyone working in drug development.

Register here 🔗 my.bps.ac.uk/events/detai...

Learn how to apply #PKPD principles in clinical and drug development settings. Join us for our training workshop 22 - 23 May in London.
🎟️ Early bird deadline: 24 April
👉 Secure your spot here: my.bps.ac.uk/events/detai...

Optimizing ceftazidime/avibactam dosing: model-based PK/PD insights to improve treatment of resistant Gram-negative infections
doi.org/10.1093/jaca...
#Antibiotics #PKPD #JACAMRNews #IDSky

➡️ More info & apply: www.mentor-program.eu

#PhD #PKPD #mTOR #DrugModeling #MarieCurie #ComputationalPharmacology #SystemsBiology

Pharmacodynamics of interspecies interactions in polymicrobial infections - npj Biofilms and Microbiomes npj Biofilms and Microbiomes - Pharmacodynamics of interspecies interactions in polymicrobial infections

👉 When do interactions between #pathogens in #polymicrobial infections alter #antimicrobial #pharmacodynamics? 🤔🦠💊 In a new paper from our group, we studied this question using computational modeling. www.nature.com/articles/s41... #AMR #PKPD #polymicrobial #ecology @unileiden.bsky.social

Animal models offer insights but require scaling to human PK/PD using physiologically based modeling to ensure accurate predictions. #TranslationalResearch #PKPD

Only unbound drugs interact with targets. High protein binding reduces free drug availability, impacting PK and PD outcomes. #DrugBinding #PKPD

Super excited to share this Breakpoints podcast episode! It was such an nice and also fun discussion! We still need to keep looking into #PKPD of ganciclovir for #CMV and I’m happy to share that we are working on that in my lab in Leiden!

Talentry

Opportunity for pharmacokinetics/pharmacodynamics (PK/PD) modeller at Boehringer Ingelheim (Vienna Austria) ref: 14335 | closing 13-Sep-2024 #DMPK #PKPD 🧪
boehringer-ingelheim.talentry.com/app/talent/s...

Preclinical and Translational PK & PKPD Scientist at AstraZeneca Learn more about applying for Preclinical and Translational PK & PKPD Scientist at AstraZeneca

Opportunity in translational pharmacokinetic-pharmacodynamic modelling at AstraZeneca (Gothenburg Sweden) ref: R-203858 | closing: 31-Aug-2024 #PK #PKPD #DMPK 🧪
careers.astrazeneca.com/job/gothenbu...

Principal Scientist (Director level) Drug Metabolism & Pharmacokinetics, London Discovery job in London, London, United Kingdom | Research & Development jobs at MSD Apply for Principal Scientist (Director level) Drug Metabolism & Pharmacokinetics, London Discovery job with MSD in London, London, United Kingdom. Browse and apply for the Research & Development jobs...

Opportunity for drug metabolism & #pharmacokinetics scientist at MSD (London UK) ref: R299041 | closing: 07-Sep-2024 (UK date format) or 09-Jul-2024 (US date format) #DMPK #PKPD #ADME #UKChemJobs #ChemJobs #chemsky 🧪 jobs.msd.com/gb/en/job/R2...

Pharmacokineticist, PK/PD Modelling & Simulation Pharmacokineticist, PK/PD Modelling & Simulation

Opportunity for pharmacokineticist in #PKPD #modelling & #simulation at Lundbeck (Copenhagen Denmark) ref: 5286 | closing 14-Jun-2024 #pharmacokinetics #DMPK 🧪jobs.lundbeck/job/Copenhagen-Pharmacok...

Monte Carlo simulation: “The results are only as good as the data you put in” - wise words from the wise James Lewis at @SHEA_Epi #pkpd

Monte Carlo simulation: “The results are only as good as the data you put in” - wise words from the wise James Lewis at @SHEA_Epi #pkpd