Discovery of vina-ginsenoside R18 as a novel dual-target inhibitor of dengue virus envelope protein and RNA-dependent RNA polymerase Vina-ginsenoside R18, acts as the first dual inhibitor of dengue virus E protein and RdRp, blocking viral entry and replication effectively

This study identifies Vina-ginsenoside R18, a #triterpenoid #saponin from #PanaxNotoginseng, as the first dual inhibitor of DENV E protein and RdRp, blocking #ViralEntry and replication, and effectively suppressing #dengue infection in vitro & in vivo.

#OpenAccess: amm-journal.org/index.php/20...