4/4
Cytokine and interferon gene expression strongly correlates with viral replication across human respiratory models.
Integrating functional data from primary human tissue with genomic surveillance is essential for pandemic risk assessment.
#PandemicPrep #SystemsBiology #H5N1

Global commitment on display as countries negotiate key annex to the Pandemic Agreement Member States of the World Health Organization (WHO) concluded a weeklong round of negotiations on draft annex for Pathogen Access and Benefit Sharing (PABS) – a key component of the WHO Pandemic Agre...

Yep, with US out of @who.int , it’s not part of #PandemicPrep agreement. As I keep saying: regime only wants “fittest” (by their beliefs that are pretty Aryan-like) to survive. www.who.int/news/item/17... #GlobalHealth #HHS #NIH #CDC

t.me/NewsInsideUk...

t.me/WorldNews/72...

Key US infectious-diseases centre to drop pandemic preparation

[Read Full Article]

@WorldNews #pandemicprep #publichealth #infectiousdisease #healthpolicy #UScenterscience

1/8 VACCINES ARE NATIONAL SECURITY, WARNS HEALTH CHIEF

Richard Hatchett (CEPI) warns that anti-vax sentiment and funding cuts threaten global safety. With the US pulling back, CEPI steps in to fill the void.

Jennifer Rigby reports.
#PublicHealth #Vaccines #NatSecSky #PandemicPrep #MedSky

India’s One Health Mission | 16 Ministries Unite to Build a National Shield Against Future Pandemics

India launches a One Health system linking human, animal and environmental surveillance.

#OneHealth #IndiaHealthSecurity #PandemicPrep #PublicHealth #IndiaUpdate

MCID & @bereadycohort.bsky.social were featured in UniAktuell and SNF Horizons! 🎉 From local funding to Europe’s only such cohort, this research shows how locally rooted, globally relevant science strengthens pandemic preparedness.

@unibe.ch @snsf.ch

#UniAktuell #Horizonte #PandemicPrep

1/11 🚨 🦠 THREE CRITICAL ACTIONS NEEDED NOW TO PREVENT AVIAN FLU PANDEMIC 🦠 🚨

H5N1 has jumped to pigs, cattle, and humans. Scientists warn time is running out.

PNAS research outlines urgent prevention measures.
#AvianFlu #PandemicPrep #H5N1

Real care looks like being ready before things fall apart.
Prep is solidarity. Prep is survival.
Prep says: I’ve got you.
#PandemicPrep #HealthJustice #Oregonizers

2/13 Researchers surveyed 6,265 Americans nationwide from August 5-15, 2024, as H5N1 cases emerged in livestock and humans.

The timing couldn't be more critical for pandemic preparedness.
#Research #PandemicPrep

6/13 The Biden administration had positioned the U.S. as a leader in pandemic preparedness.

Many countries are stockpiling vaccine components and ramping surveillance.

By halting development, "the US is essentially gambling that we won't need quick medical countermeasures."
#PandemicPrep

1/13 🚨 🇺🇸 U.S. DANGEROUSLY UNPREPARED FOR H5N1 PANDEMIC 🇺🇸 🚨

RFK Jr.'s mRNA vaccine cuts combined with weak containment leave America exposed as bird flu spreads to mammals.

Global Biodefense analysis warns of accelerating crisis.
#H5N1 #PandemicPrep #BirdFlu
#mRNA #RFKJr #PandemicRisk

6/13 mRNA's revolutionary speed advantage: Traditional flu vaccines take 5-6 months using hen's eggs. mRNA vaccines can produce millions of doses in just 6 weeks - crucial for pandemic response.
#VaccineTech #PandemicPrep

3/11 The largest cuts hit the CDC - $5.8 billion slashed from the nation's nerve center for tracking diseases and preventing deaths.

$4.7 billion cut from pandemic response. $1.1 billion from vaccination programs.

RichardJR: If H5N1 goes Pandemic it will devastate RFK Jr.'s U.S.
#CDC #PandemicPrep

9/10 "If we don't invest in technologies like mRNA vaccines for pandemic influenza now, once a virus starts going human-to-human, it will simply be too late."

Congress must restore these legally appropriated funds.
#Congress #PandemicPrep

1/10 🚨 RISK OF USHERING IN THE LARGEST MASS CASUALTY EVENT IN U.S. HISTORY 🚨

"Trump cancels $766M in mRNA vaccine contracts for H5N1"

Cornell wildlife veterinarian Steve Osofsky warns this could usher in "the largest mass casualty event in U.S. history."
#H5N1 #PandemicPrep #BirdFlu #PandemicRisk

8/9 The findings highlight a critical gap: most pandemic preparedness research still uses older, less virulent H5N1 strains from the 2000s.

Scientists urgently need updated animal models reflecting current circulating variants to test vaccines and treatments effectively.
#PandemicPrep

1/12 🦠 HOW WE'D FIGHT THE NEXT PANDEMIC: THE H5N1 RESPONSE PLAN 🦠

If bird flu mutates to spread between humans, here's the step-by-step battle plan our scientists have prepared.

A thread on pandemic preparedness from the front lines of virology 🧵
#H5N1 #PandemicPrep

"Face Masks: Separating Fact from Fiction in the Pandemic Era Discover the science behind their effectiveness, debunk common myths, and learn how to choose the right one for you #FaceMasks #PandemicPrep #Healthcare" Best Selling Make-up Products: cutt.ly/1rRrEQVF

😷 Trump admin axes NIH’s CREID network, aimed at stopping pandemics, calling it “unsafe.” $82M program to study mosquito-borne viruses & zoonotic pathogens shut down. Bad move for global health? 🦠 #TrumpHealthCuts #PandemicPrep

1/8
⚠️ BIRD FLU'S GENETIC LEAP REVEALED ⚠️

Dr. Liji Thomas reports on genomic detective work revealing how a novel H5N1 genotype jumped from wild birds to poultry—and into a human in British Columbia, raising urgent pandemic questions.
#BirdFlu #GenomicAnalysis #PandemicPrep #H5N1 #PandemicRisk

Learn how ERINHA is advancing research for pandemic preparedness in our upcoming GVN webinar with Dr. Audrey S. RICHARD! Discover this unique European high-containment lab network. Register: ow.ly/WVql50VR8AW #GVN #PandemicPrep #GlobalHealth

5/11 Researchers are already feeling the impact. Colin Carlson at Yale leads a 50-researcher pandemic prediction project funded by a $12.5 million NSF grant. He warns the freeze "is going to destroy people's labs" unless lifted soon.
#AcademicResearch #ScienceCrisis #PandemicPrep

Urgent Budget Cuts Threaten America's Public Health Future Discover alarming proposed budget cuts threatening U.S. public health, including drastic reductions to vital health agencies and research funding.

🏛️💰 Massive Health Budget Cuts Proposed: What It Could Mean for Your Health in 2025 #HealthBudgetCuts #NIH #CDC #FDA #HealthCare2025 #MedicalResearch #PublicHealthCrisis #DiseasePrevention #FoodSafety #PandemicPrep #HealthcareNews #HealthAlert #HealthNews

ultimatehealingsolutions.com/2025/04/20/%...

Building Resilient and Responsive Health Research Systems:Responses and the Lessons Learned from the COVID-19 Pandemic - Health Research Policy and Systems Background The coronavirus disease 2019 (COVID-19) pandemic highlighted the crucial role of robust health research systems (HRSs) in supporting effective public health responses. Understanding the res...

Incredibly relevant now!! New publication in Health Research Policy & Systems! We examine how health research systems responded to COVID-19 & what’s needed for future crises. Proud to lead this work.
📖 doi.org/10.1186/s129...
#HealthResearch #COVID19 #PandemicPrep #HPSR

Exclusive: NIH to cut grants for COVID research, documents reveal Studies on climate change and South Africa are also on the latest list of grants to be terminated, according to updated documents obtained by Nature.

🚨 NIH is slashing 400 research grants, including COVID-19 studies, citing the pandemic’s end!
Experts warn this move threatens future pandemic preparedness. Is the U.S. risking its own biosecurity? 🤔💰 #Science #PandemicPrep
www.nature.com/articles/d41...

UK experts urge prioritising research into 24 types of deadly pathogen families UK Health Security Agency’s tool highlights viruses and bacteria, many not yet seen in the country, that could pose biosecurity risk

🚨 UK sounds alarm on deadly pathogens! 🚨UKHSA flags 24 high-risk pathogen families urging urgent research as climate change & drug resistance fuel threats. Experts warn: diagnostic & vaccine gaps must be filled to bolster biosecurity. #GlobalHealth #PandemicPrep
www.theguardian.com/science/2025...

‘Living library’ of diseases could prevent the next Covid Porton Down, the government’s top-secret science and technology campus, is home to what may be the world’s deadliest freezer

A ‘Living Library’ to stop the next pandemic! 🦠💉 UKHSA’s Porton Down lab stores 10,000+ bacteria, viruses & fungi at -190°C, fueling research on vaccines, antibiotics & even Alzheimer’s. This hidden powerhouse could prevent the next COVID-19! 🌍🔬 #PandemicPrep
www.thetimes.com/uk/healthcar...

Structural basis of Nipah virus RNA synthesis | Nature Communications Nipah virus (NiV) is a non-segmented negative-strand RNA virus (nsNSV) with high pandemic potential, as it frequently causes zoonotic outbreaks and can be transmitted from human to human. Its RNA-dependent RNA polymerase (RdRp) complex, consisting of the L and P proteins, carries out viral genome replication and transcription and is therefore an attractive drug target. Here, we report cryo-EM structures of the NiV polymerase complex in the apo and in an early elongation state with RNA and incoming substrate bound. The structure of the apo enzyme reveals the architecture of the NiV L-P complex, which shows a high degree of similarity to other nsNSV polymerase complexes. The structure of the RNA-bound NiV L-P complex shows how the enzyme interacts with template and product RNA during early RNA synthesis and how nucleoside triphosphates are bound in the active site. Comparisons show that RNA binding leads to rearrangements of key elements in the RdRp core and to ordering of the flexi

Unveiling Nipah virus secrets! Cryo-EM reveals RdRp complex structures at 3.1Å in both apo & early elongation states. Potential drug target! #PandemicPrep PMID:40050611, Nat Commun 2025, @NatureComms https://doi.org/10.1038/s41467-025-57219-5 #Medsky #Pharmsky 🧪

Prepare now for a potential H5N1 pandemic

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Prepare now for a potential H5N1 pandemic | Science www.science.org/doi/10.1126/...

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#H5N1 #Pandemic #Science #PandemicPrep