Li et al. find that in #Paneth cells, ERAdP senses c-di-AMP derived from intestinal microbiota, activating dense core vesicle biogenesis and AMP secretion to enhance intestinal defense. rupress.org/jem/article/...

📘 In our #InnateImmunity collection: rupress.org/jem/collecti...

#KSInnateImmune26

Cunzhen Li et al. find that in #Paneth cells, ERAdP senses c-di-AMP derived from intestinal microbiota, activating dense core vesicle biogenesis and AMP secretion to enhance intestinal defense. rupress.org/jem/article/...

📘 In #Immunology Update Winter 2026 👉 rupress.org/jem/collecti...

ERAdP facilitates biogenesis of dense core vesicles in #Paneth cells to enhance intestinal defense, say Cunzhen Li, Zhen Xiong, Deyuan Kong, Yun Chen, Qiang Zhan, Zusen Fan (Institute of Biophysics, Chinese Academy of Sciences) and colleagues: rupress.org/jem/article/...

#InfectiousDisease #IBD

Cunzhen Li, Zhen Xiong, Deyuan Kong et al. find that in #Paneth cells, ERAdP senses c-di-AMP derived from intestinal microbiota, activating dense core vesicle biogenesis and AMP secretion to enhance intestinal defense. rupress.org/jem/article/...

#Microbiome #IBD #Inflammation