#Medsky🧪 #IDsky #microsky #publichealth Members of the genus #Pestivirus (family #Flaviviridae) comprise economically important livestock pathogens like classical swine fever virus (CSFV) and bovine viral diarrhea virus (BVDV). Research over recent years revealed 11 recognized & 8 proposed species.
First full genome multiple sequence alignment for the genus #Pestivirus reveals conserved #RNA structures and phylogenetic patterns across all known species, providing a key resource for #virus RNA analysis🧬
📄 www.rnajournal.org/cgi/doi/10.1261/rna.0807...
👤EVBC: Sandra Triebel, Manja Marz
🥳 New journal publication out! First full-genome alignment across all known #Pestivirus species (incl. CSFV, BVDV) 🧬💻
We identify conserved RNA elements & 29 novel #RNASecondaryStructures, expand the miR-17 landscape, and suggest a long-distance RNA interaction.
🔗 www.rnajournal.org/cgi/doi/10.1...
New Publication:
DNAJC14 gene-edited pigs are resistant to classical pestiviruses
@roslininstitute.bsky.social @thedickvet.bsky.social
#pestivirus #CRISPR
www.sciencedirect.com/science/arti...
Genome-wide comparison of all known pestiviruses uncovers conserved known and novel RNA secondary structures. #Pestivirus #RNA #alignment bit.ly/4qL3nuF
In a new study, EVBC member Sandra Triebel mapped all known #Pestivirus genomes and found 32 conserved #RNA structures that may aid diagnostics and therapies⚕️for these animal pathogens🐂🐖🦇🐪🐭🐑🦒
➡️Paper: https://doi.org/10.1101/2025.05.22.655560
➡️Blog:
🪢Viren falten ihre #RNA-Genome!
Wir haben alle #Pestivirus Genome untersucht und 32 gefaltete Strukturen entdeckt - Das könnte neue Wege eröffnen, Infektionen bei 🐖🐄🦇🐪🐭🐑🦒 zu bekämpfen.
➡️ Ganze Story im Blog: www.rna.uni-jena.de/unveiling-th...
Congrats to our #PhD student Sandra! She shared her discovery of conserved #RNA #secondarystructure features in the #Pestivirus family using a full genome alignment method at the #GfV2025 with an informative #poster