Malignant spinal cord compress (MSCC) is an oncologic emergency that impacts about 5% of patients with cancer, leading to pain, weakness, and paralysis. Let's explore the physiology, anatomy, presentation, workup and treatment.

A 🧵

#PhysiologyFriday #MedStudentSky #OncSky

Superior vena cava syndrome is a medical emergency caused by obstruction of blood flow to the SVC with malignancies causing ~60% of cases. However, with the rising use of central lines and pacemakers, the incidence is increasing.

A🧵

#PhysiologyFriday #MedStudentSky #MedSky #Skytorial #OncSky

Leukostasis is another life-threatening complication of leukemia where extremely high white blood cell counts lead to blood vessel obstruction, leading to ischemia and organ failure.

Immediate intervention is crucial.

A 🧵

#PhysiologyFriday #Skytorial #MedStudentSky #OncSky

Neutropenic fever is another oncological emergency in patients receiving chemotherapy with a high mortality rate. Let's dive into the basics!

A 🧵

#PhysiologyFriday #Skytorial #MedStudentSky #MedSky #OncSky #IDSky

Continuing our discussion on oncological emergencies from last week, let's tackle malignant hypercalcemia, which occurs in 20-30% of malignancies with a grim prognosis.

A must-know🧵 for medicine trainees!

#PhysiologyFriday #MedSky #NephSky #OncSky #Onconeph #MedStudentSky

As I gear up for residency, I've been reviewing some key medicine topics. I'm currently reviewing oncologic emergencies, starting with Tumor Lysis Syndrome.

This is high yield content on the wards and the boards, so let's dive in!

A 🧵

#PhysiologyFriday #MedSky #NephSky #MedStudentSky #Skytorial

Why do we use glucagon as an antidote in the setting of beta blocker and calcium channel blocker toxicity?

Welcome to another #PhysiologyFriday

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#MedSky #CardioSky

In an attempt to start GDMT, a 70yoF with recently diagnosed HFrEF and Stage 3b CKD is started on an ARB and a beta-blocker. A week later, she presents to the ED with bradycardia, hyperkalemia, and hypotension.

What happened?

A 🧵

#PhysiologyFriday #MedSky #CardioSky #NephSky

Thyroid Hormone Plays an Important Role in Cardiac Function: From Bench to Bedside Thyroid hormones (THs) are synthesized in the thyroid gland, and they circulate in the blood to regulate cells, tissues, and organs in the body. In particular, they exert several effects on the…

Thank you for reading this week's #PhysiologyFriday!

Sources:
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2. https://buff.ly/4geiMyB
3. https://buff.ly/3P429K8
4. https://buff.ly/4gjsxvm
5. https://buff.ly/3Dy6zWS

Hypothyroidism has various cardiovascular manifestations including arrhythmias, high blood pressure, dyslipidemia, heart failure, and pericardial effusion.

What are the physiologic mechanisms underlying these associations?

Welcome to another #PhysiologyFriday!

A 🧵

#MedSky #CardioSky

Did you know that craving specific smells, such as Pine-Sol, musty basements, gasoline, or rubber tires can be a symptom of iron deficiency anemia?

Welcome to this week's #PhysiologyFriday, a 🧵 on desiderosmia.

#MedSky #Skeetorial

Have you ever heard the adage that poinsettias are poisonous to pets? What does the science actually say?

Welcome to another #PhysiologyFriday!

A 🧵

#Skeetorial #MedSky #VetSky

Hope you enjoyed another #PhysiologyFriday thread!

References:
1. pubmed.ncbi.nlm.nih....
2. pmc.ncbi.nlm.nih.gov...
3. www.colgate.com/en-u...
4. southspringsdentalgr...
5. kaken.nii.ac.jp/en/g...
6. www.sensu.co.uk/why-....

Episode 30: Why do some people taste soap when they eat cilantro? For this episode, we dove back into the culinary world. In Episode 9 we examined the mechanisms of umami flavor and in Episode 18 we learned about thirst. For this episode we asked why some people …

I hope you found this interesting! Thank you for reading this week's #PhysiologyFriday post!

References:

1. curiousclinicians.co...
2. flavourjournal.biome...
3. link.springer.com/ar...
4. pubmed.ncbi.nlm.nih....
5. pubs.acs.org/doi/10....
6. www.compoundchem.com...