#PoloLikeKinase1 overexpression🐭->
#ChromosomalInstability #Aneuploidy #Ployploidy #Senescence in #BreastCancer
⏫SASP (IL1RN/IL6/CXCL1)
⏫PD-L1
Reshaped immune niche:
⏫Treg⏫Dendritic cell⏫Arg1+TAM⏬NK

PLK1-hi👤breast tumors->⏫Immunopressive features

#CellRep 2023
www.sciencedirect.com/science/arti...