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Holistic genetic barcoding reveals a lineage tree of tissue macrophage development Tissue macrophages are crucial for organ development and homeostasis, yet the developmental routes leading to tissue macrophages remain controversial. By combining unbiased Polylox barcoding with comp...

🎉 Next preprint on its way!
#Polylox #barcoding + computational modelling meets #macrophage #development!

We used 𝐮𝐧𝐛𝐢𝐚𝐬𝐞𝐝 𝐏𝐨𝐥𝐲𝐥𝐨𝐱 𝐛𝐚𝐫𝐜𝐨𝐝𝐢𝐧𝐠 to trace thousands of embryonic progenitor clones and map their development into tissue-specific macrophages.

Happy reading!
doi.org/10.1101/2024...

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