Rapid amyloid-β clearance and cognitive recovery through multivalent modulation of blood–brain barrier transport

LRP1-targeted multivalent #Polymersomes reprogram BBB transport, inducing #Amyloidβ clearance & achieving sustained cognitive recovery in #AlzheimersDisease models by biasing LRP1 trafficking toward #Transcytosis. @ucl.ac.uk @icta-uab.bsky.social

#OpenAccess: doi.org/10.1038/s413...

#LRP1‑targeted #polymersomes reprogram #BloodBrainBarrier trafficking, enabling rapid #Amyloidβ clearance and sustained cognitive recovery in #AlzheimersDisease models. @beppebattaglia.bsky.social @ucl.ac.uk @icta-uab.bsky.social

#CoverPage in #STTT: doi.org/10.1038/s413...