Happy to re-share Giacomo Pedrelli's paper published in PNAS with contributions from a few of us from the Vorobieva lab:
"Negative design enables cell-free expression and folding of designed transmembrane β-barrels"
#proteindesign #denovodesign #nanopores #TMBs #OMPs #porins #membraneproteins
#Proteindesign
Job of the day · 17.04.26
Bioinformatics Expert – Genomics & AI Workflow Optimization | $85/hr Remote - LinkedIn (Bioinformatics Careers)
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Industry news of the day · 17.04.26
Vir Biotechnology (VIR) Valuation After Astellas Partnership And New VIR 5500 Trial Milestone - simplywall.st
Vir Biotechnology (VIR) Valuation After Astellas Partnership And Ne...
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AI news of the day · 17.04.26
OpenAI goes after Google DeepMind's turf with a new biology-focused AI model: GPT-Rosalind - Neowin
OpenAI goes after Google DeepMind's turf with a new biology-focused AI model: GPT-R...
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Paper of the day · 17.04.26
From Atoms to Fragments: A Coarse Representation for Efficient and Functional Protein Design.
Although deep learning has accelerated protein de...
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Job of the day · 16.04.26
Arcadia Science - Platform Scientist: Protein Evolution - Lever (Lever)
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Industry news of the day · 16.04.26
Investigational New Drug CDMO Market Forecast Points Higher Toward 2035, Driven by Biologics Complexity - IndexBox
Investigational New Drug CDMO Market Forecast Points Higher To...
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Paper of the day · 16.04.26
Evaluating zero-shot prediction of monomeric protein design success by AlphaFold, ESMFold, and ProteinMPNN.
De novo protein design has enabled the crea...
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Job of the day · 15.04.26
CBS - Postdoctoral Position: Artificial Intelligence Applied to Multi-Omics Data Integration - Academic Positions (Academic Positions)
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Industry news of the day · 15.04.26
Partner Therapeutics announces submission of supplemental Biologics License Application (sBLA) to FDA for BIZENGRI® (zenocutuzumab-zbco) in NRG1 Fusion Positive Cholangiocarcino...
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AI news of the day · 15.04.26
BRIC-National Institute of Immunology opens PhD admissions for monsoon session; apply here - MSN
BRIC-National Institute of Immunology opens PhD admissions for monsoon session; apply...
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Paper of the day · 15.04.26
Binding Affinity and Interaction Profiles of Erinacines and Erinacerins with iNOS and NF-κB Revealed by Molecular Dynamics Simulations.
Chronic...
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Job of the day · 13.04.26
Bioinformatician / Bioinformatics Research Fellow at St George's, University of London - Jobs.ac.uk (Jobs.ac.uk)
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Industry news of the day · 13.04.26
Pasqal and True Nexus Partner to Optimize Alternative Protein Design via Quantum Computing - Quantum Computing Report
Pasqal and True Nexus Partner to Optimize Alternative Prote...
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AI news of the day · 13.04.26
IDEAYA Biosciences to Announce Topline Results from Phase 2/3 OptimUM-02 Trial in Metastatic Uveal Melanoma on Monday, April 13, 2026 - The Malaysian Reserve
IDEAYA Biosciences to Ann...
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Paper of the day · 13.04.26
De novo protein design: a transformative frontier in clinical protein applications.
Background Protein biologics are indispensable in disease...
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Job of the day · 07.04.26
BioSpace hiring Senior Scientist I - Bioinformatics, Biotherapeutics and Genetic Medicine in Worcester, MA - LinkedIn (Bioinformatics Careers)
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AI news of the day · 07.04.26
Cryo-EM system broadens access to structural biology - Labmate Online
Cryo-EM system broadens access to structural biology Labmate Online
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Paper of the day · 07.04.26
Salt Bridge Builder: Using Residue Distances to Predict Salt Bridge Formation.
Salt bridges contribute disproportionately to protein folding st...
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There’s a lot of hype around #AI & #proteindesign, but there are some important considerations—including how these molecules perform in laboratory conditions, says IPI's platform director André Teixeira.
Read more from Teixeira in this Science Arena article ➡️
Job of the day · 06.04.26
Computational Scientist, Computational Biology and Machine Learning - Hematology & Medical Oncology - LinkedIn (Bioinformatics Careers)
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AI news of the day · 06.04.26
We don’t adopt move fast, break things mentality to AI: DeepMind’s Kohli at HTLS - MSN
We don’t adopt move fast, break things mentality to AI: DeepMind’s Kohli at HTLS MSN
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Paper of the day · 06.04.26
Quantum chemical, spectroscopic, molecular docking, molecular dynamics analyses and ADMET properties: Nifedipine.
Nifedipine is known as a calc...
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Industry news of the day · 03.04.26
Tamarind Bio Partners with A-Alpha Bio to Streamline Experimental Validation for AI-Enabled Antibody Discovery - GlobeNewswire
Tamarind Bio Partners with A-Alpha Bio to Streamli...
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AI news of the day · 03.04.26
Introducing ROCKET: An Upgrade to AlphaFold That Learns From Raw Experimental Data - Simons Foundation
Introducing ROCKET: An Upgrade to AlphaFold That Learns From Raw Experimental Da...
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Paper of the day · 03.04.26
AlphaFold for Docking Screens.
AlphaFold is an AI system developed by Google DeepMind to generate three-dimensional structures of proteins w...
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Industry news of the day · 02.04.26
Orionis Biosciences Appoints Dr. Giulio Draetta as Chief Strategy Officer - citybiz.co
Orionis Biosciences Appoints Dr. Giulio Draetta as Chief Strategy Officer cit...
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AI news of the day · 02.04.26
Introducing ROCKET: An Upgrade to AlphaFold That Learns From Raw Experimental Data - Simons Foundation
Introducing ROCKET: An Upgrade to AlphaFold That Learns From Raw Experimental Da...
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#ProteinDesign #StructuralBiology #Bioinformatics #ProteinEngineering
Paper of the day · 02.04.26
Molecular Dynamics Simulations: Principles, Algorithms, and Emerging Applications
Molecular dynamics (MD) simulation is a fundamental te...
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AI news of the day · 01.04.26
Thermo Fisher Scientific Introduces Glacios 3 Cryo-TEM for Structural Biology Labs - Lab Manager
Thermo Fisher Scientific Introduces Glacios 3 Cryo-TEM for Structural Biology Labs &nb...
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