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Comprehensive Physiology | #TuesdayTips
📢 Call for papers: #Liver–Lung Interactions in Health & Disease
Seeking research on liver–lung cross-talk as it relates to #PulmonaryDisease, #inflammation, and#VascularRemodeling.
Visit: https://ow.ly/acLS50Yt6ZZ

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Comparative lung images from BALB/c mice infected with different MAC isolates, showing varying degrees of tissue damage. Representative lung slices display inflammation (in green) and granulomas (in red), with MAC101 and MAC104 infections showing larger affected areas than MAC2285R. Multi‑scale panels include whole‑lung views and higher‑magnification sections highlighting lesion severity and distribution.

Comparative lung images from BALB/c mice infected with different MAC isolates, showing varying degrees of tissue damage. Representative lung slices display inflammation (in green) and granulomas (in red), with MAC101 and MAC104 infections showing larger affected areas than MAC2285R. Multi‑scale panels include whole‑lung views and higher‑magnification sections highlighting lesion severity and distribution.

Timothy Shaw, Mercedes Gonzalez-Juarrero & co investigated Mycobacterium avium complex isolate-dependent differences in #PulmonaryDisease, quantified them and added novel insights into #lung immune cell profiling and whole-body plethysmography in prolonged infection.

Read doi.org/10.1242/dmm....

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Why Stubborn Lung Infections Persist Despite Therapy Whole genome sequencing reveals frequent strain acquisition and adaptive evolution of Mycobacterium avium during chronic infection, highlighting virulence and resistance targets for intervention.

🧬 Understanding stubborn lung infection: a new study reveals how M. avium frequently reinfects, evolves and resists therapy in chronic pulmonary disease, highlighting critical challenges for clinicians.

www.emjreviews.com/en-us/amj/re...

#AMJRespiratory #InfectiousDiseases #PulmonaryDisease #NTM

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Management of Nontuberculous Mycobacterial Pulmonary Disease Refractory to Guideline-Based Therapy: A Systematic Review
Aguiar, A., Akkerman, O. W. et al.
Paper
Details
#NontuberculousMycobacteria #PulmonaryDisease #GuidelineBasedTherapy

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Prevalence and Clinical Correlates of Radiologically Detected Coronary Artery Disease in Chronic Obstructive Pulmonary Disease: A Cross-Sectional Observational Study

@atscommunity.bsky.social #CoronaryArteryDisease #PulmonaryDisease

www.atsjournals.org/doi/full/10....

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3/6 Key Findings:

⚠️ CPA primarily linked with:

• Pulmonary disease (aOR 16.79, p = 0.0097)
• Emergency procedures (aOR 11.63, p = 0.0035)
• General anesthesia (aOR 19.41, p = 0.0254)
• Sedation (aOR 13.04, p = 0.0108)

#Anesthesia #PulmonaryDisease

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