Postbac positions available in experimental and computational biology working on #virusevolution, tick-borne viruses and computational drug discovery! Reach out if you’d like to discuss projects in the #QVEU at NIH-NIAID. Please share with any talented undergrads or MS students you know!

Comparative analysis of deep mutational scanning datasets in enteroviruses A and B identifies functional divergence and therapeutic targets - Nature Ecology & Evolution A comparison of proteome-wide mutational scanning datasets from enterovirus A and B species reveals evolutionary constraints shared by these viral species that localize to core functional regions, as ...

www.nature.com/articles/s41...

Excited to have this collaboration from #QVEU and @rongellerlab.bsky.social lab out in the world! After publishing our own #DeepMutationalScanning studies on two related viruses, we asked what we learn from comparisons of such datasets. The answer is a lot!

My first #QVEU postdoc, William @williambakhache.bsky.social is off to start his group at labex-netrna.cnrs.fr/presentation... in Strasbourg, FR. We’ll miss his leadership and friendship, but I’m so excited to see what he’s got planned. If you want to book a ticket on this rocketship, reach out! 🦠🧪

Constraint in West Nile Virus Envelope Protein across Mosquito, Human, and Avian Host Cell Environments Abstract. Arthropod-borne viruses are a major cause of global viral infections, displaying evolutionary dynamics that differ significantly from vertebrate-

New in ‘Virus Evolution’ from #QVEU! PhD student Jack Dorman used deep mutational scanning to measure evolutionary constraints on the Envelope protein of West Nile Virus in human, mosquito, and bird cell lines, doing a lot of work to put it into a structural context #VirEvol

Genotype-by-Inhibitor Interactions to Dissect Enterovirus Replication Replication organelles of positive-sense RNA viruses are essential to virus biology, yet their molecular mechanisms remain poorly defined. While deep mutational scanning (DMS) measures the impact of m...

New #QVEU preprint! @williambakhache.bsky.social used our #EV71 mutational scanning library to dissect replication complex function with a collection of inhibitors against specific host and viral factors. Then used the data to validate structural predictions! Super cool #virosky #virus #evolution

Walker shows us powdery mildew on plants at NIH

Walker shows us a mutant arabidopsis that is susceptible to many other host species’ powdery mildews.

Powdery mildew on… milkweed?

Lab on their field trip to find mildew specimen across the walkway from our building.

First ever #QVEU lab “field trip” during group meeting as @orrwalk.bsky.social told us all about his summer research on powdery mildew! Fascinating!

#ASV2025 in Montreal was a great success, I had a lot of fun. See you in Minnesota! Congrats to @orrwalk.bsky.social and Jack Dorman for representing the #QVEU so well.