#Reelin -LRP8 signaling mediates brain dissemination of breast #CancerCells via abluminal migration.

#zebrafish

By H. Huang, M. Zhang, E. Huang, G. Ning, J. Zhang & colleagues at Hospital of Guangdong Medical University

🗞️ doi.org/10.1038/s443...

Immunocal®, a cysteine-rich whey protein, rescues reelin and reduces amyloid plaque burden in a transgenic amyloid-β protein precursor (hAβPPSweInd) mouse model of Alzheimer's disease - PubMed BackgroundDeficits in Reelin expression play a significant role in the pathogenesis of various neurological disorders, including schizophrenia and Alzheimer's disease (AD). Notably, Reelin-expressing ...

Immunocal®, a #cysteine-rich whey protein, rescues reelin and reduces #amyloid plaque burden in a transgenic amyloid-β protein precursor (hAβPPSweInd) mouse model of Alzheimer's disease

#psychiatry #reelin #Alzheimers #Alzheimer #neuroscience #mice pubmed.ncbi.nlm.nih.gov/40325994/

#ProQR another nice gain-of-function #RNAediting patent app, this time inspired by a human genetic variant in the #reelin gene conferring 'extreme resistance' to #Alzheimer's.

Shared molecular signature in Alzheimer's disease and schizophrenia: A systematic review of the reelin signaling pathway The Reelin signaling pathway, particularly the RELN-APOER2-DAB1 complex, has emerged as a key contributor to the neuropathology of Alzheimer’s disease…

Shared molecular signature in #Alzheimer’s disease and #schizophrenia: A systematic review of the #reelin signaling pathway

www.sciencedirect.com/science/arti...

Intraneuronal binding of amyloid beta with reelin-Implications for the onset of Alzheimer's disease - PubMed Numerous studies of the human brain supported by experimental results from rodent and cell models point to a central role for intracellular amyloid beta (Aβ) in the onset of Alzheimer's disease (AD). ...

A new hypothesis on interaction of #reelin and amyloid beta in #Alzheimer's disease #dementia pubmed.ncbi.nlm.nih.gov/39775030/

And in my heart, I can't contain it
The anthem won't explain it
A world that sends you #reelin'
From decimated dreams ( #PublicDream #FinnegansWake )
Your misery + hate will kill us all!
So paint it black + take it back
Let's shout it loud + clear
Defiant to the end we hear the call
#ElectricTorah

I tell people I got a treadmill to lose weight. I really got it to help me poop.
#backed up like the crossbronx expy
#reelin' in the years
#the pageantry never stops