Had a great time seeing old friends and making some new one's. Thanks Austin #smbe17

#SMBE17 Don't miss Miguel's talk today! "..Paleogenomic evidence of gradual domestication in a 5,300 yo crop" 12:30p

Cordaux: Many XY to ZW transitions (vice versa) in pill bugs and pervasive Wolbachia #smbe17

Cordaux: Can determine if sex chromosomes are recent and functional on the basis of genetic crosses btwn fem. males and females #smbe17

Cordaux: Can Wolbachia be driving turnover of sex chromosomes in arthropods? #smbe17

Richard Cordaux:Wolbachia gene transfer into nuclear genome of pill bugs acting as a neo W #smbe17

Kristin Lee: Detecting convergence using pop genomic data making use of neutral variation at linked sites #smbe17

Storz: Mutational bias may better explain parallel changes in avian Hbs (corr w/ CpG sites) #smbe17

Storz: Sequence context (sign epistasis) limits incidence of adaptive parallel changes in hemoglobins #smbe17

Storz: Many parallel changes have no impact on Hb function. Parallel changes do not imply adaptive changes #smbe17

Storz: High altitude adaptation often involves same physiological shifts but not the same underlying substitutions #smbe17

Storz: Most convergent increases in Hb oxygen affinity not due to the same substitutions esp. as genetic distance increases #smbe17

Storz: Single substitution increases oxygen affinity in high altitude bird populations in two duplicate hemoglobins #smbe17

Jay Storz: Epistasis can reduce the prevalence of parallel change as divergence increases #smbe17

Hahn:Hemiplasy risk factor takes into account lengths of branches above & below nodes of interest. Code to be released #smbe17

Hahn: Discordance creates parallel changes and explains decreases in convergence with genetic distance #smbe17

Hahn:Species tree can be the wrong tree to use when there is a lot of hybridization: Gene tree can be better See anopheles #smbe17

Hahn:Ecolocation in bats: 60% of underlying gene trees support convergent evolution 40% do not #smbe17

Matthew Hahn:Not a single individual gene tree matches genome wide tree in wild tomatoes due to incomplete lineage sorting #smbe17

Kawamura: Each NWM species has species-specific OR repertoire; gain/loss of bitter receptor less than ORs #smbe17

Kawamura: What about at a finer timescale? Targeted gene capture of ORs in NWMs suggests pseudogene no. follows phylogeny #smbe17

Shoji Kawamura: OR pseudogene number in mammals does not correlate with dimensions of color vision #smbe17

Assis: Selection appears to have removed nested pairs with similar expression levels #smbe17

Assis: Nested genes are highly diverged in gene expression supporting transcription interference hypothesis #smbe17

Wexler: Female cockroach sex differentiation affected by transformer ; all male broods result from RNAi #smbe17

Judy Wexler: Sex differentiation of cockroach males via doublesex but no male dsx splice variant #smbe17

Lewontin lab reunion at #smbe17 with my old lab mate Spencer Wells

Mackay: Implications: Models of maintenance of standing quantitative genetic variation need modification #smbe17

Mackay: Mutation accumulation lines:too little variation to explain gene expression by neutrality Stabilizing selection? #smbe17

Mackay: Implications: Complex epistasis and pleiotropy make predicting phenotype from genotype difficult #smbe17