Two structures of Legionella pneumophila serogroup 1 peptide deformylase (PDF) provide insight into PDF inhibition and support continued anti-PDF drug-development efforts #SSGCID #StructuralGenomics #>PeptideDeformylases doi.org/10.1107/S205...

Apo and dUMP-bound structures of Legionella pneumophila dUTPase revealed a potential new binding site and active-site structural differences when compared with human dUTPase #SSGCID #StructuralGenomics doi.org/10.1107/S205...

The structure of Helicobacter pylori biotin protein ligase reveals a conserved catalytic cavity and structural similarity to the Mycobacterium tuberculosis enzyme, which is promising for repurposing inhibitors #UndergraduateEducationAndTraining #SSGCID #InfectiousDiseases doi.org/10.1107/S205...

The distinct active-site architecture of Burkholderia cenocepacia short-chain dehydrogenase (SDR) suggests that it is most appropriately classed as a divergent SDR #ResearchExperiencesForUndergraduates #SSGCID doi.org/10.1107/S205...

Two structures of Brucella ovis leucine-, isoleucine-, valine-, threonine- and alanine-binding protein are reported that show its conformational flexibility in the absence of bound amino acids
#SSGCID #StructuralGenomics #Brucellosis t.co/aDI9PPMCdu

Three crystal structures of two NAD(P)H nitroreductases from Klebsiella pneumoniae are presented and an analysis of their structures and their flavin mononucleotide-binding mode is provided. #Nitroreductase #SSGCID #StructuralGenomics t.co/0dFO1nRWzB