C. elegans highlights potential molecular determinants involved in O. vulgaris nociception. Data for the drop assay is reported here as the number of actual reversals after exposure to the noxious cue (M9, pH 3). The heat map shows a colour coded indication of the strains' sensitivity to M9, pH 3 from non-sensitive che-3 (e1124)-like (magenta) to sensitive WT N2-like (green). Each colour block represents the average number of reversals across all the worms tested per strain. The WT N2 performance was characterised by at least three body reversals within 5 s of contact with the drop and was used to set our criteria for responsiveness.
An animal's ability to detect and withdraw from noxious stimuli is crucial for its survival and is mediated by nociceptors. Here, Pieroni & co venture into finding molecular candidates for nociceptors in Octopus vulgaris. 🐙 doi.org/10.1242/bio....
#Nociception #SensoryCues #Octopus
