Physiological and injury-induced microglial dynamics across the lifespan Tieu, T. et al. leveraged in vivo two-photon live imaging of microglia, the brain’s resident immune cells, to reveal striking differences in their morphology, basal dynamics, and injury responses acro...

#NewResearch from the #VcoelhoSantosLab and #ShihLab used #two-photon live imaging to reveal how #microglia 🧠 evolve across across #lifespan.

Key findings:
👶 Neonatal: Active but clumsy
🧍‍♂️ Adult: Calm but sharp
👵 Aged: Quiet and slow

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