Systematic characterization of PBP2 as the primary siderophore recognizer in Actinomycetes and other Gram-positive bacteria Iron is a scarce yet essential nutrient for bacteria. Microbes often acquire iron by secreting siderophores, a diverse group of small molecules that form high-affinity complexes with iron for microbia...

One more piece towards the microbial "IronNet": In G+ bacteria, the PBP2 receptor is the siderophore-specificity determinant. But, it can be located half a genome away from the synthetase. The solution? Transcriptional co-regulation: doi.org/10.1099/mgen... #Genomics #Siderophore

Photodecarboxylation of the Siderophore Aerobactin with the Lewis Acidic Metal Ions Fe(III), Ga(III), and Ti(IV) | Inorganic Chemistry pubs.acs.org/doi/10.1021/... @e_boros and co-workers @InorgChem #iron #gallium #titanium #siderophore #photodecarboxylation

Interestingly, I've largely abandoned X. However, I posted our recent siderophore article on both sites as I had a larger footprint in the #ChemBio, #siderophore, and #naturalproduct communities that I haven't quite reconstructed here.

So, if you're into interested, go look for our latest.

Thanks for the digest, @elife.bsky.social 💥
How to combat pathogenic bacteria through iron starvation:
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#AMR #Siderophore

The Staphylococcus aureus-antagonizing human nasal commensal Staphylococcus lugdunensis depends on siderophore piracy - Microbiome Background Bacterial pathogens such as Staphylococcus aureus colonize body surfaces of part of the human population, which represents a critical risk factor for skin disorders and invasive infections....

Nose bacterium S. lugdunensis can outcompete pathogenic S. aureus

How can this be used to prevent infection?

What can we learn from that about microbial interaction in microbiomes?

Article just published in the journal Microbiome!

link.springer.com/article/10.1...

#Microbiome #Siderophore #MRSA

New NIOO publication: #Cultivar governs plant response to #inoculation with single isolates and the #microbiome associated with arbuscular mycorrhizal #fungi, by @C_Rotoni @MarcioLeiteEco @KuramaeEiko and others. #siderophore...