Inflammation and B cell activation define a plasma proteome signature predicting tuberculosis in people with HIV | mBio We still lack reliable tools to predict who will develop tuberculosis (TB) among people with HIV. Moreover, the underlying biological events driving progression remain poorly understood. Our study reveals early immune changes that include unexpected ...

The full open-access paper is now out in mBio:
journals.asm.org/doi/10.1128/...

#USZ #HIV #Tuberculosis #Proteomics #MachineLearning #SwissHIVCohort #Biomarkers #Immunology

Published in PLOS Pathogens with Marius Zeeb and Alexandra Trkola. These results deepen our understanding of HIV/MTB co-infection and open paths for novel immunological diagnostics.

#Immunology #HIV #Tuberculosis #HostPathogen #USZ #AdaptiveImmunity #SwissHIVCohort