TH17 cells converted into exTH17 cells sustain rheumatoid-like IL-17–independent inflammatory arthritis ExTH17 cells drive IL-17–independent chronic SKG arthritis in mice through up-regulation of CD44 and S1PR4 and cross-talk with FLS.

www.science.org/doi/10.1126/...

📖”Through a lineage-tracing approach, they detected conversion of synovial TH17 cells to CD44+ IFN-γ−IL-10− exTH17 cells, which are arthritogenic and cause joint inflammation independent of IL-17. “

#Th17 #arthritis

THANK YOU #TOBINHEATH

Your love and dedication for the game inspired and continues to inspire so many around the world.

Congratulations on a remarkable career.

You returned the gift of playing soccer but you've made space for so many new and amazing things.

#TH17 #WOSO #TOBIN #LEGEND #RE-INC

Today, Michelle Montoya from @uvaimmunology.bsky.social will present a #preprint on how Serpine1 plays a critical role in #Th17 cell differentiation and #psoriasis pathogenesis. 🐭🙌☝️

www.biorxiv.org/content/10.1...

Anthelmintic Drugs as Emerging Immune Modulators in Cancer Despite recent advances in treatment approaches, cancer is still one of the leading causes of death worldwide. Restoration of tumor immune surveillance represents a valid strategy to overcome the acqu...

www.mdpi.com/1422-0067/24...

"Flubendazole also interferes with #STAT3 activity, as well as with the function/differentiation of T helper (Th)-17 cells and regulatory T-cells," #Treg #Th17

Level 100 archer queen 😎👍 #ClashofClans #TH17