@russellrogers.bsky.social discussed experiments w/Lefer Lab taking advantage of the mechanistic differences between #GLP1RA & #ncRNA #TY1 as therapeutics for #HFpEF. Compelling evidence for synergistic benefits in two rodent models! Potential for less skeletal muscle loss?
@smidtheart.bsky.social

Stimulating #labmeeting today by #postdoc Salwa Soussi, PhD on #aging and how it is modulated by novel #RNAdrug #TY1. Strong evidence for central role of #cGAS #STING in cardiac #senescence. Animated discussion followed!