😊 Lovely work in @ScienceMagazine by Hayashi group on building a #testis from stem cells.
📝 Check out this perspective* on how this could one day help us to restore fertility in males 🙏
👉 tinyurl.com/mrx49fjz
The paper can be viewed here 👉 tinyurl.com/3853y5m9
Somatic sex maintenance in the Drosophila testis. Left: in XY adults, chinmo prevents Zld protein expression, keeping traF off and allowing dsxM to maintain the male fate (blue) while the female pathway is switched off (gray). Right: loss of chinmo leads to the ectopic expression of zld, inducing traF and activating the female developmental program (red) in chromosomally male cells.
In the #gonad, #sex is not an irrevocable commitment, and requires active maintenance. Artyom Kopp explores a new @plosbiology.org study elucidating the molecular mechanisms that preserve sexual identity in the adult #Drosophila #testis 🧪 Paper: plos.io/4pMT6hq Primer: plos.io/3MRBBxG
Somatic sex maintenance in the Drosophila testis. Left: in XY adults, chinmo prevents Zld protein expression, keeping traF off and allowing dsxM to maintain the male fate (blue) while the female pathway is switched off (gray). Right: loss of chinmo leads to the ectopic expression of zld, inducing traF and activating the female developmental program (red) in chromosomally male cells.
In the #gonad, #sex is not an irrevocable commitment, and requires active maintenance. Artyom Kopp explores a new @plosbiology.org study elucidating the molecular mechanisms that preserve sexual identity in the adult #Drosophila #testis 🧪 Paper: plos.io/4pMT6hq Primer: plos.io/3MRBBxG
Somatic sex maintenance in the Drosophila testis. Left: in XY adults, chinmo prevents Zld protein expression, keeping traF off and allowing dsxM to maintain the male fate (blue) while the female pathway is switched off (gray). Right: loss of chinmo leads to the ectopic expression of zld, inducing traF and activating the female developmental program (red) in chromosomally male cells.
In the #gonad, #sex is not an irrevocable commitment, and requires active maintenance. Artyom Kopp explores a new @plosbiology.org study elucidating the molecular mechanisms that preserve sexual identity in the adult #Drosophila #testis 🧪 Paper: plos.io/4pMT6hq Primer: plos.io/3MRBBxG
Representative confocal images of a control testis (top row), a testis somatically depleted of chinmo (middle row), and a testis with somatic co-depletion of chinmo and zld (bottom row). Testes are stained for Vasa (gray), Fas3 (green, grayscale), and Tj (magenta).
How is somatic gonadal #sex fate maintained throughout adulthood? This study identifies a post-transcriptional mechanism involving repression of the TF Zelda by #miRNAs, safeguarding male identity & preventing activation of the female program in #Drosophila #testis @plosbiology.org 🧪 plos.io/4pMT6hq
Representative confocal images of a control testis (top row), a testis somatically depleted of chinmo (middle row), and a testis with somatic co-depletion of chinmo and zld (bottom row). Testes are stained for Vasa (gray), Fas3 (green, grayscale), and Tj (magenta).
How is somatic gonadal #sex fate maintained throughout adulthood? This study identifies a post-transcriptional mechanism involving repression of the TF Zelda by #miRNAs, safeguarding male identity & preventing activation of the female program in #Drosophila #testis @plosbiology.org 🧪 plos.io/4pMT6hq
Representative confocal images of a control testis (top row), a testis somatically depleted of chinmo (middle row), and a testis with somatic co-depletion of chinmo and zld (bottom row). Testes are stained for Vasa (gray), Fas3 (green, grayscale), and Tj (magenta).
How is somatic gonadal #sex fate maintained throughout adulthood? This study identifies a post-transcriptional mechanism involving repression of the TF Zelda by #miRNAs, safeguarding male identity & preventing activation of the female program in #Drosophila #testis @plosbiology.org 🧪 plos.io/4pMT6hq
#pecs #fitspiration #bodycheck #bulge #Male #musclecock #muscle #master #Masterbate #AlphaMale #cum #cock #nutsack #bigballs #testis
Glittering art in the Jewellery Quarter Birmingham by #artist DeniseBallard-Wyllie ARE in the talented @re_printmakers at the RBSA Gallery, Birmingham 7-18 October
Enjoy creativity, collect unique art for your home
#scienceart #womanartist #testis #affordableart #cells
artistdenisewyllie #buyart
睪丸 ( #Testis )：
Testis
接收上述賀爾蒙後，
開始啟動精子發生，
並透過睪固酮促進精子的成熟、維持男性第二性徵 ( 如聲音低沉、
體毛增加 )。
#Bolas #Pelotas #Escroto #Hoden #яечка #тестис #Testis #Testicle #Varle #Pinga #Barrabil #Testicule #όρχις #Zaadbal #Testicolo #Testikolu #testikkel #अंडा #Butt #tèstikul #тестис #testikkel #Balls #Holle #Pack #Butts #Huevos #Testicles #Nutts #Pelotas #Güevos #Cojones #Canicas
A fantastic talk from Grace about #chemotherapy exposure in the #testis 👏🏼👏🏼 So important for protection of #fertility in #ChildhoodCancer 🎗️
Lovely talk from @GraceForsyth13 on an in-vivo model for chemotherapy exposure in the #testis. Important work for developing strategies for #FertilityPreservation 👏🏻👏🏻👏🏻
https://www.sciencedirect.com/science/article/pii/S0032579125003803
Oral administration of #probiotic LbSNI3 enhances #antioxidant defense mechanisms in the #testis, leading to increased #reproductive index in adult roosters. This effect may be mediated through the #gut-testis axis and could be utilized to improve productivity in livestock industry.
Simplify your assessment of #ovarian and #testicular volumes with our #gonadal volume calculator, now equipped with a report generator! Streamlined for efficiency.
#radiology #RadTwitter #ovary #testis #ultrasound #radres #radfellow
