Ubiquitin-specific protease 13 promotes colorectal cancer progression by stabilizing mitogen-activated protein kinase kinase 3 - Molecular Biomedicine The deubiquitinase ubiquitin-specific protease 13 (USP13) has been implicated in various cancers, yet its precise molecular function and clinical significance in colorectal cancer (CRC) remain poorly ...

#Research
Ubiquitin-specific protease 13 promotes colorectal cancer progression by stabilizing mitogen-activated protein kinase kinase 3 doi.org/10.1186/s435...

#ColorectalCancer #USP13 #MKK3 #P38 #MAPK #signaling #Deubiquitination #TumorProgression

This review highlights the role of #SLC7A11 in #Tumorigenesis through modulating ferroptotic responses, emphasizing its potential as a #therapeutic target to suppress #TumorProgression. #medsky

#OpenAccess: www.sciencedirect.com/science/arti...

This study identifies a #CDC20 inhibitor, Apcin, as a key molecular driver in #EndometrialCarcinoma that significantly suppresses #TumorProgression, thus opening new possibilities for targeted therapeutics approaches. #medsky

Read more: link.springer.com/article/10.1...