Palmdelphin, a risk gene for #CalcficAorticValveDisease & highly enriched in #ValvularEndothelium,
protects against #HighFatDiet-induced decline of Aortic Valve Structure+Function

Palmdelphin binds to TNIP1/GDF15/JAK1 ➡️ TNF & NFκB signals

#JACCBTS 2023
www.sciencedirect.com/science/arti...