High-fat diets cause gut bacteria to enter the brain – BioNews Central A recent study conducted in mice shows that live bacteria from an imbalanced gut microbiome can directly enter the brain via the vagus nerve, potentially impacting neurological health. ...

A recent study conducted in mice shows that live #bacteria from an imbalanced #GutMicrobiome can directly enter the #brain via the #VagusNerve, potentially impacting #NeurologicalHealth. 
#GutBacteria #HighFatDiet #GutDysbiosis #GutBrainConnection #GutBrainAxis #BrainHealth

#SIRT6 #VascularCalcification

Rat #HighFatDiet + VitD3 + Nicotine
▶️Aortic medial calcification & ⏬SIRT6

SIRT6 overexpression ⏬Palmitic acid-induced #SmoothMuscleCell Apoptosis & Osteogenesis

#JHyperten 2023
journals.lww.com/jhypertensio...

High-fat diets make liver cells more likely to become cancerous – BioNews Central A high-fat diet causes mature liver cells to revert to an immature, stem-cell-like state, increasing their survival under stress but also raising the risk of liver cancer. ...

A #HighFatDiet causes mature #LiverCells to revert to an immature, #StemCell -like state, increasing their survival under stress but also raising the risk of #LiverCancer. 
#MetabolicStress #LiverCancerRisk

Makes you wonder what is considered "junk food" by these states, since a good deal of the "regular" benefit offerings could well be considered Junk Food 🙄
#highfatdiet

Smell of fatty foods during pregnancy promotes obesity in offspring – BioNews Central A mouse study found that the smell of fatty foods during pregnancy increases the risk of overweight and obesity in offspring, which develop stronger reactions to a high-fat diet and show signs of insulin resistance. ...

A mouse study found that the #smell of #FattyFoods during #pregnancy increases the risk of #overweight and #obesity in #offspring, which develop stronger reactions to a #HighFatDiet and show signs of #InsulinResistance.
#PrenatalExposure

#EndothelialCell #MerTK #Efferocytosis #Atherosclerosis

EC MerTK KO🐭+ AAV8-PCSK9 + #HighFatDiet 2-mo
👉⏫lesion burden
👉⏫NADPH oxidase
👉⏫inflamm cytokines

Aortic Arch lesion #Proteomics➡️
⏫TGFβ HIF1α Wnt3a IL2
⏬LARP1 NAMPT TEAD1

Zufeng Ding lab #RedoxBiol 2025
www.sciencedirect.com/science/arti...

High‑Fat Diet Can Impair Memory in Just One Week, Study Finds

A week of a high‑fat diet (20% coconut oil) reduced middle‑ and long‑term memory in fruit flies, while immediate recall stayed normal; reactivating autophagy restored memory. getnews.me/high-fat-diet-can-impair... #highfatdiet #memory #autophagy

mRNA profiles of FGF family 22 ligands + 10 (co)receptors in♂️🐭
Heart Liver Kidney Skeletal muscle Gonadal/s.c. WAT BAT

young 7-wk vs aged 12-mo
-/+ #HighFatDiet

Effect of HFD
FGF9 ⏫in BAT, ⏬ in kidney of young, not aged🐭

Effects of #Aging
↔️FGF9

#JEndocrSoc 2025
academic.oup.com/jes/article/...

#HighFatDiet (60% fat w/o extra cholesterol or cholic acid) protects Marfan Aortopathy in♀️, not♂️, mgR/mgR🐭
⏬thoracic aortic diameter
⏬elastin fragmentation
⏬MMP12 Col1a1
↔️proteoglycan

Any benefit on Lifespan or #AorticDissection?😃

#AortaEd
#CJC 2023
onlinecjc.ca/article/S082...

High-fat diet promotes breast cancer metastasis in animal models – BioNews Central New research shows that a high-fat diet and platelet activation influence the metastasis of triple-negative breast cancer cells, suggesting potential new treatments and prognostic markers. ...

New research shows that a #HighFatDiet and #PlateletActivation influence the #metastasis of #TripleNegativeBreastCancer cells, suggesting potential new #treatments and #PrognosticMarkers.
#BreastCancer

Just Three Days on a High-Fat Diet Can Harm Your Brain A new study finds that saturated fat can impair memory and cause brain inflammation in as little as three days.

Just Three Days on a High-Fat Diet Can Harm Your Brain #Science #HealthandMedicine #Nutrition #BrainHealth #DietImpact #HighFatDiet

A Florida Man’s Meat, Cheese, and Butter Diet Caused His Hands to Seep out Cholesterol Doctors published a case report this week detailing a rare complication linked to adopting an extreme high-fat

A Florida Man’s Meat, Cheese, and Butter Diet Caused His Hands to Seep out Cholesterol #Technology #Health #Nutrition #HighFatDiet #HealthComplications #CarnivoreDiet

A new paper just out in PLoS One looking at how a #HighFatDiet can influence #Cardiac #Electrophysiology and the role of NOX2. Congrats to the Authors and thanks to the Reviewers!

#CardioSky

journals.plos.org/plosone/arti...

#MetabolicFlexibility #FastingForHealth
#LowCarbLiving #HighFatDiet #MetabolismBoost #NutritionalScience #TherapeuticFasting #NutritionalMetabolism #EnergyMetabolism #NutritionAndHealth
#CellularHealth #MetabolicBalance

We are hiring! We are looking for a motivated postdoctoral fellow to work on an exciting project on #Metastasis and #HighFatDiet at #CABIMER in the beautiful city of Seville (Spain). Join us! More info 👇

Antioxidants combat high-fat diet-induced female reproductive issues, study reveals Researchers in Italy review how antioxidants from biological matrices can protect against reproductive issues caused by high-fat diets in women.

Antioxidants combat high-fat diet-induced female reproductive issues, study reveals news-medical.net/news/2024061... #FemaleFertility #HighFatDiet #Antioxidants #ReproductiveHealth #Nutrition #OxidativeStress #WomensHealth #FertilityResearch #Ovaries #Diet

Father's diet before conception can impact children's metabolic health, study finds Research reveals that a father's high-fat diet can influence offspring's metabolic health through changes in sperm mitochondrial RNA, potentially leading to glucose intolerance.

Father's diet before conception can impact children's metabolic health, study finds 🧬🍔👶 www.news-medical.net/news/2024060... #MetabolicHealth #Epigenetics #HighFatDiet #PaternalInfluence #Sperm #RNA #Mitochondrial #GlucoseIntolerance #Offspring #Health #Diet @natureportfolio.bsky.social

High-fat diet accelerates aging-related memory loss in rats Study found that a high-fat diet exacerbates age-related cognitive decline in rats, even when microglia cells are removed from the equation, suggesting other pathways may play a role.

High-fat diet accelerates aging-related memory loss in rats 🧠📉🍔 www.news-medical.net/news/2024050... #MemoryLoss #Aging #Brain #HighFatDiet #Obesity #Cognition #CognitiveImpairment #Neuroscience #BrainHealth #Aging #Diet #BrainFunction