Integrative Mechanisms of Osteoprotegerin in Cardiovascular Pathophysiology Summarizing the molecular and clinical insights on the multifaceted role of Osteoprotegerin in cardiovascular diseases.

This #CVIA review describes osteoprotegerin as a key regulator of #VascularHomeostasis and #Inflammation, demonstrating that dysregulation of the OPG/RANKL/TRAIL axis drives #ArterialCalcification and adverse #CardiacRemodeling.

#OpenAccess: cvia-journal.org/osteoprotege...

This review explores how #HistoneDeacetylases regulate #VascularHomeostasis via endothelial and smooth muscle cells, highlighting their role in vascular #Pathogenesis and the therapeutic potential of #HDACinhibitors.

#OpenAccess: doi.org/10.1016/j.ge...