#SpatialTranscriptomics #Visium #VeinGraft #Neointima

Late-stage Neointimal cells in grafted vessels are More Contractile & Synthetic than regenerated Medial cells

FHL1 CRISPR KO Rat▶️hyper-inflammatory, dysmorphic intima

Clin Transl Med 2024
onlinelibrary.wiley.com/doi/full/10....

#VeinGraft #SpatialTranscriptomics #Visium

Amazing transcriptomic changes of🐶cephalic vein induced by 30-min Distension (papaverine+bivalirudin)

Matrix-organizing #SmoothMuscleCell⏬ ~50% in distended vein😬 (is this a reason for #VeinGraftFailure?)

#CircRes 2024
www.ahajournals.org/doi/10.1161/...