Estrogen-responsive cells found to heighten gut pain in females Researchers uncovered how estrogen heightens gut sensitivity in females by activating PYY-secreting L-cells, which stimulate serotonin release from EC cells. This paracrine circuit intensifies pain si...

Estrogen-responsive cells found to heighten gut pain in females 🧠🧬🌿 www.news-medical.net/news/2025061... #Estrogen #Gut #Health #Pain #WomensHealth #IBS #Neuroscience #Microbiome #Hormones #VisceralPain #SCFA @biorxivpreprint.bsky.social

An interorgan neuroimmune circuit promotes visceral hypersensitivity Visceral pain disorders such as interstitial cystitis/bladder pain syndrome (IC/BPS) and irritable bowel syndrome (IBS) often manifest concurrently in the bladder and colon. Yet, the mechanistic basis...

#itchdoctor Exciting study from the Kim Lab on how mast cells and sensory neurons drive cross-organ pain 💥🧠 #VisceralPain #NeuroImmune #IBS #ICBPS www.researchsquare.com/article/rs-6...

#Gut–#Brain🧠axis #Pain signalling mechanisms in #GI tract‼️ #GutPain
✅Most recent advances on molecular communication between non-neuronal cell types & #neurons in #VisceralPain
🎯Huge potential of #Neuromodulation in #DGBIs👏
👉https://nature.com/articles/s41575-024-01017-9
@natrevgastrohep.bsky.social