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A scoping review of grey zone use for transfusion‐transmitted infection screening among blood donors Background and Objectives Screening for transfusion-transmitted infections (TTIs) among blood donors is done using qualitative screening assays. Screening values that are close to cut-off values lie...

New in #VoxSanguinis

The review explores the use of the “grey zone” in transfusion-transmitted infection (TTI) screening among blood donors.

doi.org/10.1111/vox....

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Assessment of services for diagnosis, management and prevention of thalassaemia in India: The way forward Reader environment loaded

India has one of the world’s largest populations with #thalassemia major - a new article in #VoxSanguinis highlights key insights on diagnosis, management, and prevention.

Essential reading for healthcare professionals, policymakers, and anyone working in #thalassemiacare

🔗 doi.org/10.1111/vox....

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Seroprevalence of hepatitis D virus among blood donors with hepatitis B surface antigen at Yaounde Central Hospital, Cameroon Background and Objectives Hepatitis delta virus (HDV) superinfection with hepatitis B virus (HBV) infection can cause a severe form of viral hepatitis. A nation-wide general population study in Came...

Recently shared in #VoxSanguinis: Seroprevalence of Hepatitis D Virus among HBsAg-positive blood donors at Yaoundé Central Hospital, Cameroon.

The report highlights a high prevalence of HDV in asymptomatic blood donors and shows that anti-HDV detection depends on the HBsAg screening method.

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Association between group B major ABO‐incompatible platelet or plasma transfusion and severe allergic reactions: A nationwide haemovigilance analysis suggesting a role for α‐gal syndrome. A Biomedical... Background and Objectives Severe transfusion reactions to group B–incompatible platelets and plasma possibly related to the α-gal syndrome (AGS) have been recently described. AGS is a potentially se.....

Recently published in #VoxSanguinis

• Group B or AB platelets/plasma transfused to group O recipients carry a ⬆ risk of severe allergic reactions.
• Risk is stronger with platelets than plasma, potentially linked to α-gal syndrome.

Use ABO-identical platelets/plasma for group O whenever possible.

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Assessing the effect of policy change on transfusion safety in Brazil: A three‐and‐a‐half‐year study after lifting the deferral for men who have sex with men Background and Objectives In July 2020, Brazil removed the long-standing restrictions on blood donation by men who have sex with men (MSM), shifting donor eligibility criteria towards individual beh.....

New in #VoxSanguinis: Brazil’s policy lifting the MSM blood donor deferral didn’t raise HIV, HBV, or HCV rates across 560K+ donations.

Syphilis rise in first-time donors mirrors broader trends—public health strategies matter

onlinelibrary.wiley.com/doi/abs/10.1...

#BloodSafety #PublicHealth

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Exploring low haemoglobin density as a no‐added‐cost screening marker to assess iron deficiency Background and Objectives Iron deficiency (ID), with or without anaemia, affects over 1 billion people globally. Early detection is essential, but current diagnostic tools may be costly, logisticall.....

New research in #VoxSanguinis explores low haemoglobin density (LHD%) as a no-added-cost marker for screening iron deficiency.

Accessible, scalable, and derived from routine CBC data.

🔗 onlinelibrary.wiley.com/doi/full/10....

#Haematology #IronDeficiency #Anaemia

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New in #VoxSanguinis: A BEST Collaborative study reviews red blood cell (RBC) quality assessment methods.

lnkd.in/eHhedRUp

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Risk of transfusion‐transmitted infections among returned high‐risk deferred donors: A cohort study Background and Objectives Blood donor selection is crucial for ensuring safe blood supply. A well-designed donor selection system helps in maintaining donor engagement by minimizing unnecessary excl...

A recent study in #VoxSanguinis shows that returned high-risk deferred donors in Iran face a significantly higher risk of transfusion-transmitted infections (TTIs) compared to eligible donors.

onlinelibrary.wiley.com/doi/abs/10.1...

#BloodSafety #TransfusionMedicine #MedicalResearch #PublicHealth

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Recently published in #VoxSanguinis: Autoantibodies in COVID-19 convalescent plasma donors

🔗 Read the full article here: https://doi.org/10.1111/vox.70140

#TransfusionMedicine #ISBT #VoxSanguinis

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Recently published in #VoxSanguinis: Nucleic acid testing in Colombian blood banks (2018–2024): Implementation, yield estimates and implications for safer transfusion policy

🔗 Read the full article here: https://doi.org/10.1111/vox.70130

#TransfusionMedicine #ISBT #VoxSanguinis

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Vox Sanguinis turns 70! 🎉✨

For 70 years, Vox has been at the forefront of scientific discovery, fostering knowledge and collaboration that have shaped Transfusion Medicine worldwide.

Look at the journal's history: https://onlinelibrary.wiley.com/doi/10.1111/vox.70170

#ISBT #VoxSanguinis

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Check out this recently published article in #VoxSanguinis: Potential benefits of an alternative haemoglobin deferral strategy evaluated in seven countries

🔗 Read the full article here: https://doi.org/10.1111/vox.70131

#TransfusionMedicine #ISBT #VoxSanguinis

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Recently published in #VoxSanguinis: Assessment of Leishmania Exposure in Blood Donors from a Non-Endemic Urban Area: A Study in São Paulo

🔗 Read the full article here: https://doi.org/10.1111/vox.70146

#TransfusionMedicine #ISBT #VoxSanguinis

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Recently published in #VoxSanguinis: Multinational transfusion practices and outcomes in hematology patients admitted to the Intensive Care Unit

🔗 Read the full article here: https://doi.org/10.1111/vox.70153

#TransfusionMedicine #ISBT #VoxSanguinis

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Recently published in #VoxSanguinis: Practices in Platelet Production: A Nordic Perspective (2018–2022)

🔗Read the article here: https://doi.org/10.1111/vox.70163

#TransfusionMedicine #ISBT #VoxSanguinis

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Recently published in #VoxSanguinis: In vitro quality assessment of red blood cells and plasma units in DEHT/SAGM bags and DEHT/PAGGSM bags during storage

🔗Read the article here: https://doi.org/10.1111/vox.70151

#TransfusionMedicine #ISBT #VoxSanguinis

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Analysis of haemovigilance reports reveals 12.5% of acute haemolytic transfusion reactions are attributed to antibodies to low‐incidence antigens Background and Objectives Many transfusion centres no longer perform an antiglobulin crossmatch on patients without clinically significant red cell alloantibodies, but instead use an abbreviated cro...

New in #VoxSanguinis: Analysis of haemovigilance reports reveals 12.5% of acute haemolytic transfusion reactions are attributed to antibodies to low-incidence antigens

🔗 Read the article here: doi.org/10.1111/vox....

#TransfusionMedicine #ISBT #VoxSanguinis

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RhD‐negative red blood cell use and conservation strategies in the Region of Southern Denmark Background and Objectives Suboptimal use of RhD-negative red blood cells (RBCs) can lead to reduced inventories of this scarce resource. Prevention of D-alloimmunization is particularly important fo...

New in #VoxSanguinis: RhD-negative red blood cell use and conservation strategies in the Region of Southern Denmark

🔗 Read the full article here: doi.org/10.1111/vox....

#TransfusionMedicine #ISBT #VoxSanguinis

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New #VoxSanguinis: Machine Learning–Enhanced Digital Microscopy for Personalized Assessment of Red Blood Cell Storage Lesions🩸

A new study presents a machine learning platform for rapid, quantitative evaluation of red blood cell aging.

🔗 Read more: doi.org/10.1111%2Fvo...

#ISBT #VoxSanguinis

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Beyond the human eye: Artificial intelligence revolutionizing plasma quality control You have to enable JavaScript in your browser's settings in order to use the eReader.

New article in #VoxSanguinis: Beyond the Human Eye: Artificial Intelligence Revolutionizing Plasma Quality Control

💡94.7% accuracy and 100% sensitivity
💡Detected all abnormal units
💡Significantly reduced normal plasma wastage

🔗 Read the article here: doi.org/10.1111%2Fvo...

#ISBT #VoxSanguinis

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#VoxSanguinis: Manufacturing stresses do not differentially impact red blood cells from donors with diabetes

💡Blood manufacturing does not differentially impact red blood cells from donors with type 1 or type 2 diabetes.

🔗Read the full article here: onlinelibrary.wiley.com/doi/10.1111/...

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Partial D variant with demonstrated risk of D alloimmunization in the Australian Indigenous population You have to enable JavaScript in your browser's settings in order to use the eReader.

New in #VoxSanguinis: Partial D variant with demonstrated risk of D alloimmunisation in the Australian Indigenous population

💡This article reports a novel RHD variant.

Read more: onlinelibrary.wiley.com/doi/epdf/10....

#Transfusion #BloodResearch

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Neocyte‐enriched blood does not provide a survival advantage for red cells when compared to conventional filtered blood Background and Objectives Red blood cell (RBC) concentrates are stored at 1–6°C for up to 42 days, but storage lesions can lead to wastage. Pooled neocytes may extend RBC shelf-life, benefiting pati...

New in #VoxSanguinis:
Neocyte-enriched blood doesn’t extend RBC survival vs. conventional filtered blood in chronic transfusions.

💡 Time to reassess its value & cost-effectiveness.

Read more: onlinelibrary.wiley.com/doi/full/10....

#BloodTransfusion #Hematology #SickleCell #Thalassaemia

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New in #VoxSanguinis!

A simple, extraction-free genotyping method: heat whole blood at 95°C for 5 mins to get a PCR-ready template—no DNA extraction needed.

✅ One-tube protocol
✅ Saves time & cost
✅ Reliable for HPA genotyping

onlinelibrary.wiley.com/doi/abs/10.1...

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Prophylactic high‐dose granulocyte transfusions following allogeneic haematopoietic stem cell transplantation Background and Objectives Prophylactic granulocyte transfusions (PGTxs) are controversial. Previous studies faced numerous confounders such as achieving an adequate dose. Pre-emptive or secondary PG...

New in Vox Sanguinis:
High-dose prophylactic granulocyte transfusions (PGTx) after allogeneic stem cell transplant were well tolerated and boosted neutrophil counts during neutropenia.

🔗 onlinelibrary.wiley.com/doi/abs/10.1...
#Transfusion #Haematology #StemCell #PGTx #VoxSanguinis

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Forecasting emerging trends in transfusion medicine through complex network analysis of scholars' research You have to enable JavaScript in your browser's settings in order to use the eReader.

New in #VoxSanguinis:
"Forecasting Emerging Trends in #TransfusionMedicine"
A network analysis of research reveals clinical transfusion at the core, with growth in management, platelet/plasma use, and emerging focus on personalized therapies, #immunohaematology & cell-based treatments.

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The need for routine detection of the Asian‐type DEL allele in individuals with weak or partial D phenotypes from East and Southeast Asian populations You have to enable JavaScript in your browser's settings in order to use the eReader.

New in #VoxSanguinis: Routine detection of the Asian-type DEL (RHD*DEL1) allele is recommended for individuals of East/Southeast Asian ancestry with weak or partial D phenotypes.

🔗 onlinelibrary.wiley.com/doi/epdf/10....

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Management strategies and clinical outcomes of obstetric patients who decline allogeneic blood transfusion Background and Objectives Providing obstetrical care for patients who decline transfusions can be challenging. We describe methods of coordinated bloodless care and compare outcomes to a similar gro...

New in #VoxSanguinis: Obstetric care without #transfusion—safe & effective.

This study outlines specialized strategies for patients who decline allogeneic blood:
0 deaths in either group
Low morbidity: 1.5% (bloodless) vs 0.8%
Multidisciplinary care is key

onlinelibrary.wiley.com/doi/abs/10.1...

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Characterization of the in vitro quality parameters of cold‐stored platelets containing aggregates Background and Objectives Cold-stored platelets (CSP) are being used more widely for the treatment of bleeding because of their longer shelf life. However, storage at low temperatures can induce the...

#VoxSanguinis A closer look at cold-stored #platelets and the presence of aggregates.

• Aggregates were present in ~10% of cold-stored units
• These platelets showed increased activation
• Standard filtration didn’t eliminate all aggregates
onlinelibrary.wiley.com/doi/full/10....

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Why men who have sex with men in New Zealand intend to donate or not donate blood Background and Objectives As blood donor deferral policies in many countries transition from blanket time-based approaches towards individualized risk-based approaches, blood services need to unders...

New in #VoxSanguinis
Why do some men who have sex with men #MSM in New Zealand choose to donate—or not donate—blood?

This study explores the motivations, mistrust, and cultural considerations shaping #blooddonation decisions among MSM in NZ.

onlinelibrary.wiley.com/doi/full/10....

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