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For patients with Parkinson's disease experiencing troublesome "wearing off" motor fluctuations with oral medications, continuous subcutaneous levodopa/carbidopa infusions offer a promising alternative.
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Most brain abscesses among meningitis patients were caused by pneumococci, but non-pneumococcal streptococci had the highest risk for abscesses. Patients with abscesses had a high risk for an unfavourable outcome.
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6) A skeletal muscle MRI should be performed to guide/interpret genetic testing
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Despite their massive impact on overall health and an economic burden in the hundreds of billions of Euros, sleep disorders remain critically neglected in public health strategies
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The incidence of Myasthenia Gravis in patients over 65 is rising, yet it often faces substantial diagnostic delays due to overlapping comorbidities.
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Patients undergoing cardiac surgery for #InfectiveEndocarditis who have preoperative neurological complications remain at a high risk for postoperative neurological deterioration.
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Cranial nerve involvement serves as a diagnostic clue in chronic autoimmune neuropathies, particularly in identifying AN and CIDP. Cranial+ CIDP appears to represent a distinct subset with partial overlap to GBS.
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Patient-centered communication and a structured clinical framework are vital for improving diagnostic confidence and therapeutic engagement in Persistent Postural-Perceptual Dizziness (PPPD)
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Clinicodemographic factors help predict MS treatment outcomes, but adding Neurofilament light chain (NfL) concentrations provides minimal extra predictive value.
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Check out the February issue of European Journal of Neurology!
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❤️ Early implantation of an internal loop recorder after cryptogenic stroke significantly improves the detection of silent paroxysmal atrial fibrillation compared to standard care.
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🧠 Deep Brain Stimulation outcomes in monogenic dystonia are highly dependent on genetic etiology.
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In a nationwide Danish comparative effectiveness study of RRMS, no significant differences were found between Ocrelizumab and Natalizumab regarding relapse rates, disability progression (PIRA), or MRI activity.
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📚 Read the recently published article “Muscle MRI Contributes to the Differential Diagnosis Between Distal Myopathies and Distal Hereditary Motor Neuropathies” by Payá & Portela et al. now: onlinelibrary.wiley.com/doi/10.1111/...
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😶🌫️ Patients with disorders of consciousness in focal brainstem injury show significant global reductions in brainstem-cortical white matter projections, particularly in the frontoparietal network.
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Multimodal MRI serves as an accurate tool for detecting CNS damage in Hereditary Transthyretin Amyloidosis with polyneuropathy, highlighting the need for early monitoring beyond peripheral nerves.
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🧬 CES combined with HPO-based filtering is an effective strategy for suspected HSP, achieving a diagnostic yield of nearly 53%. While SPAST and SPG7 remain the most common mutations.
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📝 Call for Papers on Environmental Influences in Neurology
Submission deadline: 31 August 2026
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Be part of shaping the future of high‑quality neurology publishing.
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Check out the January issue of European Journal of Neurology!
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📚 Read the recently published article “The Association Between Detailed Obesity Measurements and Peripheral Neuropathy in Persons With Diabetes” by Reynolds et al. now: onlinelibrary.wiley.com/doi/10.1111/...
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CSF-specific oligoclonal bands have a high sensitivity and specificity and a very high negative predictive value for diagnosing MS. However, the positive predictive value was lower in this cohort.
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SARS-CoV-2 infection was strongly associated with new-onset headache. Primary vaccination was associated with a small increased risk of headache during a low-transmission period, whereas booster offered protection on high-transmission
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In a recently published clinical trial, tablet-assisted speech and language therapy showed potential benefits in patients with mild to moderate aphasia and less severe strokes in the acute setting.
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A recently published article in the European Journal of Neurology argues that a decline in proximal CMAP amplitude may not indicate true motor conduction block.
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📚 Read the recently published article “Clinical and Laboratory Predictors of Poor Neurological Outcomes Following Infectious Encephalitis: Systematic Review and Meta-Analysis” by Johnson et al. now: onlinelibrary.wiley.com/doi/10.1111/...
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GCA should be considered in IS/TIA patients ≥ 50 years with vertebrobasilar or multiterritorial involvement, or recurrent IS/TIA despite secondary prevention.
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New-onset FND appears more likely after COVID-19 than other respiratory tract infections. Both the severity of the triggering illness and pre-existing individual vulnerability may contribute to the development of FND.
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Sleep abnormalities, bulbar dysfunction and movement disorders were most frequently reported in Anti-IgLON5 disease.
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