Two new drugs give clinicians hope against gonorrhea The quest to contain gonorrhea has been a decades-long struggle, but there is hope on the horizon in the form of new medications, clinicians said.In December, the FDA approved the first two new antibiotics for gonorrhea in nearly 40 years: Blujepa (gepotidacin, GSK) and Nuzolvence (zoliflodacin, Innoviva Specialty Therapeutics). With these, clinicians look to take the upper hand on a pathogen —

🚨Approvals of #gepotidacin and #zoliflodacin come at a vital juncture, with #gonorrhea building resistance to other antibiotics. “There’s great hope and enthusiasm in the STI community for these new treatment options,” says a prominent physician .

vist.ly/4tx22

Two new drugs give clinicians hope against gonorrhea The quest to contain gonorrhea has been a decades-long struggle, but there is hope on the horizon in the form of new medications, clinicians said.In December, the FDA approved the first two new antibiotics for gonorrhea in nearly 40 years: Blujepa (gepotidacin, GSK) and Nuzolvence (zoliflodacin, Innoviva Specialty Therapeutics). With these, clinicians look to take the upper hand on a pathogen —

🚨Armed with #gepotidacin and #zoliflodacin, clinicians now look to take the upper hand on #gonorrhea, which has ducked and dodged nearly every antibiotic used for treatment.

vist.ly/4ttiv

New research article

Microbiological analysis and whole-genome sequencing of #Neisseria gonorrhoeae from the microbiological failures in the … #zoliflodacin … trial for treatment of uncomplicated urogenital #gonorrhoea

www.thelancet.com/journals/lan...

#IDSky #ClinMicro #STI #AMR #OpenAccess #OA

Great to see the #zoliflodacin paper.

With #gepotidacin, we have TWO new antibiotics to use for #gonorrhea! 🎉

But big Qs about use and access remain, esp in Asia Pacific, where ceftriaxone resistance is already sky high (nearly 30% in 🇻🇳)
#IDSky #STIsky #AMR

🔗: www.thelancet.com/journals/lan...

Screenshot of paragraphs 7-10 of the linked article

"New #gonorrhea drug is not just a scientific breakthrough but a business one - A not-for-profit R&D model will let #zoliflodacin reach people who need it most"
www.statnews.com/2025/12/17/z...

Wow - decision even sooner than expected.

Great news - #zoliflodacin is now licenced - the only drug that can only be used for #gonorrhoea

But Nuzolvence? Who invents these names 🤣?

New antibiotic for gonorrhea could help beat back drug-resistant infections Two treatments for the sexually transmitted disease are expected to become available soon

🧪 #Zoliflodacin a truly new #antibiotic just for #gonorrhoea

Maybe even more important is the controversial debate about how best to use it

We work with UZH, @yhgrad.bsky.social and @gardp.bsky.social to model the best strategies in 🇿🇦

@ispm.unibe.ch @unibe.ch

www.science.org/content/arti...

👏 Henry #Zoliflodacin #gonorrhoea 🇿🇦 🇹🇭 🇳🇱 🇺🇸 🌎

Do read @kakape.bsky.social in @science.org news

"One important aspect of the trial is that the majority of patients came from low- and middle-income countries, where most cases—and the highest burden of complications —occur"
bsky.app/profile/nico...

Zoliflodacin: Positive Phase-III-Daten für neues Antibiotikum Zoliflodacin ist ein neuartiger Gyrasehemmer, der in einer Phase-III-Studie seine Nicht-Unterlegenheit gegenüber der Standardtherapie bei Gonorrh&ouml...

#Zoliflodacin ist ein neuartiger Gyrasehemmer, der in einer Phase-III-Studie seine Nicht-Unterlegenheit gegenüber der Standardtherapie bei #Gonorrhö unter Beweis gestellt hat. In den USA läuft das Zulassungsverfahren, in Europa allerdings noch nicht.

This is a great 🧵 and a great team.

Always getting ahead of the curve on thinking about #gonorrhoea #AntimicobialResistance and new drugs #zoliflodacin #gepotidacin

Looking forward to hearing more in Montreal
@stihiv2025.org

Gegen "Super-Tripper" – Ceftriaxon- und/oder Azithromycin-resistente Gonorrhö-Stämme – ist ein neues Antibiotikum gefunden: #Zoliflodacin.