Two new drugs give clinicians hope against gonorrhea The quest to contain gonorrhea has been a decades-long struggle, but there is hope on the horizon in the form of new medications, clinicians said.In December, the FDA approved the first two new antibiotics for gonorrhea in nearly 40 years: Blujepa (gepotidacin, GSK) and Nuzolvence (zoliflodacin, Innoviva Specialty Therapeutics). With these, clinicians look to take the upper hand on a pathogen —

🚨Approvals of #gepotidacin and #zoliflodacin come at a vital juncture, with #gonorrhea building resistance to other antibiotics. “There’s great hope and enthusiasm in the STI community for these new treatment options,” says a prominent physician .

vist.ly/4tx22

Two new drugs give clinicians hope against gonorrhea The quest to contain gonorrhea has been a decades-long struggle, but there is hope on the horizon in the form of new medications, clinicians said.In December, the FDA approved the first two new antibiotics for gonorrhea in nearly 40 years: Blujepa (gepotidacin, GSK) and Nuzolvence (zoliflodacin, Innoviva Specialty Therapeutics). With these, clinicians look to take the upper hand on a pathogen —

🚨Armed with #gepotidacin and #zoliflodacin, clinicians now look to take the upper hand on #gonorrhea, which has ducked and dodged nearly every antibiotic used for treatment.

vist.ly/4ttiv

FDA Approves First New Gonorrhea Treatments In 30 Years After decades of relying on a single injection, doctors finally have two new weapons.

From #ESCMID2025 - The first-in-class antibacterial #gepotidacin is noninferior to the standard first-line option in people with uncomplicated urogenital #gonorrhea.

Full story 👉 buff.ly/dEWuVrB

#MedNews

Great to see the #zoliflodacin paper.

With #gepotidacin, we have TWO new antibiotics to use for #gonorrhea! 🎉

But big Qs about use and access remain, esp in Asia Pacific, where ceftriaxone resistance is already sky high (nearly 30% in 🇻🇳)
#IDSky #STIsky #AMR

🔗: www.thelancet.com/journals/lan...

This is a great 🧵 and a great team.

Always getting ahead of the curve on thinking about #gonorrhoea #AntimicobialResistance and new drugs #zoliflodacin #gepotidacin

Looking forward to hearing more in Montreal
@stihiv2025.org

EAGLE-1 trial offers hope of new oral treatment for gonorrhea The first-in-class antibacterial gepotidacin is noninferior to the standard first-line option in people with uncomplicated urogenital gonorrhea.

From #ESCMID25 - The first-in-class antibacterial #gepotidacin is noninferior to the standard first-line option in people with uncomplicated urogenital #gonorrhea.

Full story 👉 buff.ly/EWVHEkT

#MedSky #STIs #UroSky

Antibiotic could help tackle drug-resistant gonorrhoea, study results suggest Gepotidacin, a first-in-class triazaacenaphthylene antibiotic, has shown non-inferiority to first-line treatment ceftriaxone plus azithromycin and potentially offers “a novel oral treatment option…

In a study of more than 600 patients, researchers found that #gepotidacin was as effective as #ceftriaxone plus #azithromycin, the current recommended first-line therapy for #gonorrhoea

buff.ly/0ICc0IY

Phase-III-Studie: Gepotidacin wirksam gegen Gonorrhö Antibiotikaresistente Gonorrhö ist eine globale Bedrohung. Daher werden neue Wirkstoffe dringend gesucht. Einen Kandidaten gibt es nun: Gepotidacin. Eine Frage zur Wirksamkeit bleibt aber noch offen.

#GuteNachricht: Das Antibiotikum #Gepotidacin (seit März 2025 in den USA zugelassen, noch keine EU-Zulassung) hat sich in einer Phase-3-Studie als wirksam gegen Gonokokken erwiesen, die Erreger der #Gonorrhö. Einige Gonokokken-Stämme sind bereits gegen die aktuell eingesetzten Antibiotika resistent.

Neuartiges Antibiotikum gegen Gonorrhö

Neues #Antibiotikum könnte beim Kampf gegen #Antibiotikaresistenzen helfen: #Gepotidacin gegen Gonorrhö in Phase-3-Studie in The Lancet wirksam. Forschend betonten Relevanz neuer Wirkstoffe bei #Tripper, Pharmafirma strebt Zulassung auch in Europa an: www.sciencemediacenter.de/angebote/neu...

📝Here are my cliff notes for the recently FDA approved drug #gepotidacin #blujepa

www.idstewardship.com/drugs/gepoti...

🤔 Still wondering where the name comes from? It’s a yellow tablet… Kind of sounds like Jet Blue 🤷‍♂️

Anything to add? #IDsky

+++ News Bites: Deutschlands Ruf bröckelt +++ Erster Toter durch Alaskapox-Virus, immer weniger Deutsche zählen das Gesundheitssystem zu den Top 3 und Gepotidacin liefert als neues Antibiotikum bei Harnwegsinfekten gute Ergebnisse. Diese und weit...

Erster Toter durch #Alaskapox Virus, immer weniger Deutsche zählen das #Gesundheitssystem zu den Top 3 und #Gepotidacin liefert als neues Antibiotikum bei Harnwegsinfekten gute Ergebnisse. Diese und weitere News lest ihr hier. docc.hk/wc8xgp