Antibiotic-resistant bacteria found in many healthy birthing moms and their newborns A recent study has found gut bacteria resistant to common antibiotics (ampicillin and ceftriaxone) in a sizable percentage of healthy birthing moms and their newborns. In this study, 38% of bacterial…

#Antibiotic-resistant #bacteria found in many healthy birthing #moms and their #newborns ...

| #Antibioticresistance | #microbes | #gut | #ampicillin | #ceftriaxone | Via @sciencex.bsky.social

Antibiotic Therapy for Uncomplicated Acute Appendicitis This observational follow-up of patients in the Appendicitis Acuta multicenter randomized clinical trial conducted in Finland assesses the 10-year appendicitis recurrence and appendectomy rate in adul...

10y f/u for APPAC on antibiotics vs surg for initial presentation appendicitis show that ~50% pts went onto appy w/i 10y in abx arm.

Does this change your practice/recs

#medsky #IDsky #surgery #criticalcare #sepsis #appendicitis #ceftriaxone #flagyl #zosyn #piptazo

jamanetwork.com/journals/jam...

Cefixime for the Treatment of Neisseria gonorrhoeae Infections in a Setting With Increased Antimicrobial Resistance: A Retrospective Study in Hanoi, Vietnam In Vietnam, cefixime effectively treated rectal and urethral gonococcal infections but showed higher pharyngeal NAAT positivity at test of cure (TOC) compa

#Cefixime is an alternative treatment for #gonorrhea, typically when #ceftriaxone isn’t available or feasible, but clinical data are limited, esp in areas w/ high #AMR

Here, we report outcomes from patients treated with cefixime in Hanoi 🇻🇳
🔗 academic.oup.com/cid/article/...

#STIsky #IDsky

1/

3➡️Des recommandations pour le traitement via antibiothérapie de la borréliose de Lyme.

www.sciencedirect.com/science/arti...

#IDSky #IDSkyFr #Doxycycline #Ceftriaxone #AntibioticTherapy #ChallengingTreatment #FollowUp

🧪 #Gonorrhoea #AntimicrobialResistance surveillance @who.int an enormously important resource.

But, the 5% #ceftriaxone resistance isn't a global average. 124/125 resistant isolates from Cambodia and VietNam, with known high resistance. None in 9/12 countries.

Important not to misinterpret.

New research article

Determining targets for #ceftriaxone resistance detection in #Neisseria gonorrhoeae based on genotype–phenotype data: an observational study

www.thelancet.com/journals/lan...

#IDSky #ClinMicro #AMR #gonorrhoea #gonorrhea #OpenAccess #OA

#haemophilus #influenzae #epiglottitis treatment with third generation cephalosporin #ceftriaxone

‘World-first’ gonorrhoea vaccine to be rolled out in England Jab hailed as ‘landmark moment for sexual health’ and comes amid record cases of infection

The program comes amid warnings that cases of #gonorrhea that are resistant to the antibiotic #ceftriaxone – usually the first line of treatment – are on the rise in #England. #vaccines buff.ly/kt2T4aS

Antibiotic could help tackle drug-resistant gonorrhoea, study results suggest Gepotidacin, a first-in-class triazaacenaphthylene antibiotic, has shown non-inferiority to first-line treatment ceftriaxone plus azithromycin and potentially offers “a novel oral treatment option…

In a study of more than 600 patients, researchers found that #gepotidacin was as effective as #ceftriaxone plus #azithromycin, the current recommended first-line therapy for #gonorrhoea

buff.ly/0ICc0IY

Parenteral Antibiotics: Brands & Dosages
#AmpicillinCloxacillin #Ampiclox #Benzylpenicillin #BenzathinePenicillinG #Coamoxiclav #Augmentin #Calamox #Clindamycin #DalacinC #Ceftriaxone #Rocephin #Oxidil #Inocef #Cefotaxime #Cefotax #Clarithromycin #Metronidazole #Flagyl #Abazole #VikaasLLC

#ceftriaxone #gonorrhea #IDsky when to suspect treatment failure

#Gonorrhea strain reported in Massachusetts 2024 showed resistance or reduced susceptibility to five classes of antibiotics:
1. #Ceftriaxone (a cephalosporin, currently the last widely recommended treatment).
2. #Cefixime (another cephalosporin previously used for treatment).

Ceftriaxone-induced drug reaction mimicking acute splenic sequestration crisis in a child with hemoglobin SC disease - PubMed We report a new presentation of ceftriaxone-induced drug reaction in a patient with SCD mimicking an acute splenic sequestration crisis. Review of the literature for cases of ceftriaxone-induced drug ...

#Ceftriaxone can cause severe intravascular immune hemolysis in pediatric sickle cell patients. Does this result from ceftriaxone interacting with Hb SS or from hemolysis triggering an acute SS crisis? pubmed.ncbi.nlm.nih.gov/29473172/