Aberrant Expression of A Disintegrin and Metalloproteinase With Thrombospondin Motifs 13 (ADAMTS13) in Pancreatic Cancer Leads to Dichotomic Functions Allmang et al. demonstrated that ADAMTS13 is overexpressed in PDAC, associated with prolonged survival and reduced vascular density. Knockout of ADAMTS13 in PDAC cells led to a decrease in migration ...

#Article in #MedComm
Aberrant Expression of A Disintegrin and Metalloproteinase With Thrombospondin Motifs 13 (ADAMTS13) in Pancreatic Cancer Leads to Dichotomic Functions doi.org/10.1002/mco2...

#ADAMTS13 #adipokine #pancreas #PDAC #PeripancreaticAdipose #vascularization

#HFpEF appears to develop as a result of changes in the biology of a person’s internal fat tissue, according to the #Adipokine Hypothesis, a new way of understanding how fat may impact the heart.

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#JACC #ESCCongress #WCCardio #CardioSky

SERPINA3C as a mediator of metabolic health in offspring - Nature Metabolism Exercise during pregnancy benefits both mother and child. A Nature Metabolism study identifies the adipokine SERPINA3C as crucial for enhancing metabolic health in offspring, and provides insights into the mechanisms behind maternal exercise benefits.

NEWS&VIEWS | Bianca E. Suur and Emma Börgeson ( @au.dk )

#Exercise during #pregnancy benefits both mother and child. #Maternal #exercise induced #adipokine SERPINA3C enhances #metabolic #health in #offspring 🐭

https://bit.ly/42dRrrF