Proinflammatory cytokine-induced alpha cell impairment in human islet microtissues is partially restored by dual incretin receptor agonism - Diabetologia Aims/hypothesis In type 1 diabetes, the counterregulatory glucagon response to low plasma glucose is impaired. The resulting increased risk of hypoglycaemia necessitates novel strategies to ameliorate...

New research highlights that inflammation impairs alpha cell function in human islet microtissues and how incretin receptor agonists partially restore glucagon secretion. #alphacells #islets #glucagon #cytokines #T1D #incretins link.springer.com/article/10.1... 🔓