Anticholinergic drugs tied to heart risks Curated by <b>Smartbrief</b>. A study in <a href="https://link.springer.com/article/10.1186/s12916-026-04751-w" target="_blank" rel="noopener">BMC Medicine</a> found that anticholinergic drugs, common...

Carga de anticolinérgicos aumenta el riesgo CV en adultos y adultos mayores por lo que deben prescribirse y monitorizarse con cuidado #anticholinergic #heart newsletter.smartbrief.com/sharedSummar...

Investigating the Impact of Polypharmacy and Anticholinergic Medication Burden on Objective Cognitive Performance in Adults With Multiple Sclerosis

"We hypothesized that #polypharmacy would be negatively associated with cognitive performance.... We also explored whether #anticholinergic burden scales could predict cognitive performance after controlling for relevant covariates."
doi.org/10.7224/1537...
#MultipleSclerosis #DMT

A 46% higher risk of dementia? Wow. Wasn't aware of the blockage of acetylcholine from certain OTC & prescribed drugs.

▶️ This pill is linked to dementia - Leonid Kim MD
youtube.com/watch?v=ny7M...

☑️ #Anticholinergic Drugs and #Dementia Risk - WebMD
www.webmd.com/alzheimers/w...
#alzheimers

Original post on mastodon.social

A 46% higher risk of dementia? Wow. Wasn't aware of the blockage of acetylcholine from certain OTC & prescribed drugs.

▶️ This pill is linked to dementia - Leonid Kim MD
youtube.com/watch

☑️ #Anticholinergic Drugs and #Dementia Risk - WebMD […]

In a new JCP article and podcast episode, Drs. Badre and Geier present a practical #anticholinergic #equivalence table to help clinicians assess and minimize psychotropic anticholinergic burden.

🎧 Podcast: jcpjournal.libsyn.com/anticholiner...
📰 Article: journals.lww.com/psychopharma...

In a new JCP article and podcast episode, Drs. Nicolas Badre and Eric Geier present a practical #anticholinergic equivalence table to help clinicians assess and minimize psychotropic anticholinergic burden.

🎧 Podcast: podcasts.apple.com/us/podcast/a...
📰 Article: journals.lww.com/psychopharma...

#diphenhydramine #benadryl #allergy-medication #antihistamine #allergen #allergy-symptom #safety #off-label-use #side-effect #anticholinergic #drug-reaction #alternative-treatment #pediatric-use #geriatric-use #unrecommended-drug #medication-approval

"Clinicians should consider the possible negative consequences of #polypharmacy when addressing cognitive concerns in [ #MultipleSclerosis]. #Anticholinergic burden scales may be valuable in this regard."
doi.org/10.7224/1537...

Another huge Scandinavian population registry study, this one looking at #anticholinergic drugs and #dementia risk. Conclusion- yes there is an association- but it may be reverse causation ie urinary tract symptoms could be early symptom of dementia and lead to the prescribing.

Cumulative anticholinergic exposure and white matter hyperintensity burden in community‐dwelling older adults Background Anticholinergic exposure is associated with dementia risk; however, the mechanisms for this association remain unclear. The objective of this study was to examine the association between ...

If you're using #anticholinergic sleep aids like #unisom or #benadryl consistently, be aware of the #dementia risk.

Here's more evidence that anticholinergic burden matters for #brainhealth.

Patients often don't realize this because they think over the counter = safe.

doi.org/10.1111/jgs....