New Publication:
Neanderthal-derived variants increase SOX9 enhancer activity in craniofacial progenitors that shape jaw development
@uoe-igc.bsky.social @kirstyuttley.bsky.social @hannahlong.bsky.social
#neanderthalvariants #craniofacialdevelopment
journals.biologists.com/dev/article/...
In March's #EditorsChoice, Griffin, Saint-Jeannet & co come face to face with a new #Xenopus model for a rare #SplicingDisorder
⚡ doi.org/10.1242/dmm....
📰 doi.org/10.1242/dmm....
#CraniofacialDevelopment
Cell Cycle Arrest of a "Zippering" Epithelial Cell Cluster Shapes the Face and is Disrupted in Craniofacial Disorders
Adameyko, I., Chacon, B. H. et al.
Paper
Details
#CellCycleArrest #CraniofacialDevelopment #EpithelialClusteringDisorders
Ancient genetics shape modern human traits. 🦧🧬Check out the latest #Refereedpreprint at @reviewcommons.org from the Long lab on #Neanderthal variants influencing #craniofacialdevelopment
@hannahlong.bsky.social
Referee reports and author's response
>> eeb.embo.org/doi/10.1101/2024.09.24.614243
Scientists studied stem cells from Coffin-Siris syndrome patients and used animal models (mice and chicken embryos) to uncover how ZIC2 regulates neural crest cell migration and how ARID1A loss leads to craniofacial defects.
#CraniofacialDevelopment #Genetics
🚀 FaceBase is now on BlueSky!
We are a public, NIDCR-funded data repository and resource driving innovation in dental, oral, & craniofacial (DOC) research.
Follow us for updates on datasets, events, & tools that advance science!
#CraniofacialDevelopment #Genomics #BiomedicalResearch #Bioinformatics
