Single-cell analysis reveals cell death as driver of NLRP3-mediated secretion of IL-1β in human monocytes - Nature Immunology Lamkanfi, Shirasaki, Izawa and colleagues show that IL-1β release in human monocytes stimulated with lipopolysaccharide or carrying NLRP3 activatory mutations is mostly restricted to cells undergoing…

Interleukin-1β (IL-1β) is secreted primarily by dying monocytes rather than by live bystander monocytes, challenging established models.

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#CAPS has a @RareConnect community page (). Also check out the Canadian CAPS Network (@CdnCAPSNet) on Twitter and our private FB group linked to on our website: #MWS #NOMID #FCAS #cryopyrin #raredisease

From Dr. Tim Oberg, Moran Eye Center: #raredisease #autoinflammatory #CAPS #MWS #NOMID #FCAS #rheumatology #opthalmology #cryopyrin

How to clinically #diagnose #Cryopyrin Assocated Periodic Syndromes, aka #CAPS. Also, pls follow @CdnCAPSNet if you’re interested in #autoinflammatory diseases.