Post-doctoral Positions Wanted: Talented applicants to study intercellular mRNA trafficking in vitro and in vivo and its application in RNA therapeutics Relevant works: Haimovich et al. 2017 PNAS http://www.pnas.org/content/114/46/E9873.full Dasgupta et al. 2023 eLife https://elifesciences.org/articles/83584 Haimovich et al. 2024 bioRxiv https://www.biorxiv.org/content/10.1101/2024.11.06.622258v1 Contact: Prof. Jeffrey Gerst Dept. of Molecular Genetics jeffrey.gerst@weizmann.ac.il www.weizmann.ac.il/molgen/Gerst/

💥 Reminder: 💥
We are still looking for a postdoc (we actually have enough funds for two!) to work on this promising project.
Details in the ad and the alt text
🧪 🧬 🔬 🐁
#RNASky #RNABiology #Cytoskel #TunnelingNanotubes

Pancreatic cancer cells exchange ribosomes through tunnelling nanotubes Background Pancreatic ductal adenocarcinoma (PDAC) is considered as one of the deadliest types of cancer. Tunnelling nanotubes (TNTs) are thin, membranous, intercellular communication structuresobserv...

How did I miss this preprint, posted in June?
Looks really intersting.
They suggest transfer of mRNA, ribosomes & translating ribosomes through #TunnelingNanotubes in pancreatic cancer, promoted by chemo.
Added to the reading pile.
#RNASky #RNABiology #Cytoskel 🧪🔬

www.biorxiv.org/content/10.1...

Lymphocytic choriomeningitis arenavirus utilises intercellular connections for cell to cell spread - Scientific Reports Scientific Reports - Lymphocytic choriomeningitis arenavirus utilises intercellular connections for cell to cell spread

oh nice.
A virus that is associated with fatal neurologic disease in humans is spreading between cells via #TunnelingNanotubes -like connections.
#cytoskel #virosky 🧪

www.nature.com/articles/s41...