This is very encouraging. Proving that sglt2i has an actual impact on ADPKD progression and in earlier disease will be key now. #stoppkd #dapapkd

Let‘s close the evidence gap for SGLT2i in ADPKD. Two large upcoming multicenter IITs in Europe will address this question and are described for the first time in this review.
#STOPPKD #DAPAPKD

https://academic.oup.com/ndt/advance-article/doi/10.1093/ndt/gfaf061/8108808

Just published in NDT : #SGLT2i for patients with #ADPKD – closing the evidence gap

With experts from 🇩🇪🇳🇱🇯🇵🇺🇸🇫🇷 we review:
✅ Rationale for SGLT2i in ADPKD
✅ Preclinical and observational evidence
✅ Potential disease-specific benefits and risks
✅ Ongoing/upcoming trials, incl. #DAPAPKD & #STOPPKD