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Awesome talk from @ox.ac.uk Prof. Alex Bullock @leidenscience.bsky.social today. Neat examples of #neomorphic gain-of-function mutations driving disease by acting as #molecularglues and using #FBDD to expand the #druggability of E3ligases with thesgc.bsky.social‬
and #EUbOPEN @led3hub.bsky.social

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Cornified envelope formation pathway.

Cornified envelope formation pathway.

Check our integrated meta-analysis of melanoma progression: www.mdpi.com/2075-4418/15...

#melanoma_metastasis #druggability #bioinformatics

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