Targeting extrachromosomal DNA in human cancers - Nature Reviews Drug Discovery Extrachromosomal DNA (ecDNA) drives oncogene amplification, tumour evolution and therapy resistance across cancers. This Review summarizes advances in ecDNA biology, highlights emerging therapeutic vu...

🧬 New #ecDNA @natrevcancer.nature.com review by team #eDyNAmiC @stanfordmedicine.bsky.social @scripps.edu

👉 doi.org/10.1038/s415...

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