VAMP7-dependent late endosomal secretion of ER and mitochondrial proteins impacts the tumor microenvironment and macrophage engagement - Nature Communications The SNARE VAMP7 is essential for an unconventional secretory pathway based on late endosomal secretion. Here the authors show that this secretion functions as an organelle quality-control and stress-c...

Congrats to Somya Vats et al. from team Galli and collaborators: they show that Vamp7 dependent endosomal secretion acts as quality-control mechanism, that has a particular relevance to cancer.
@inserm.fr @upcite.bsky.social #endosomes #endosomalsecretion

www.nature.com/articles/s41...