Both #ensitrelvir & #paxlovid are potent & well-tolerated antiviral treatments for early COVID . While paxlovid showed slightly faster #viralclearance, #ensitrelvir demonstrated similar efficacy.

#Medsky🧪 #IDsky #immunosky #episky #pharmsky #publichealth
Both #ensitrelvir & #Paxlovid accelerate oropharyngeal #SARSCoV2 #viralclearance. Ensitrelvir is an effective alternative to currently available antivirals in treating outpatients with #COVID.

#Antiviral efficacy of oral #ensitrelvir versus oral ritonavir-boosted #nirmatrelvir in #COVID19 (PLATCOV): an open-label, phase 2, randomised, controlled, adaptive trial

#Antiviral efficacy of oral #ensitrelvir versus oral ritonavir-boosted #nirmatrelvir in #COVID19 (PLATCOV): an open-label, phase 2, randomised, controlled, adaptive trial, etidiohnew.blogspot.com/2025/10/anti...

New antiviral application for COVID-19 preventive drug submitted to FDA Ensitrelvir, also known as Xocova, is already approved for use in Japan.

New antiviral for preventing Covid infection post-exposure applies to FDA for new drug authorization. Already in use in Japan and Singapore. #ensitrelvir #xocova #publichealth www.cidrap.umn.edu/covid-19/new...

#Ensitrelvir was associated with scores that were points higher on day 4, 3.5 points higher on day 7, & 2.0 points higher on day 14 vs symptomatic treatment . The results demonstrated that

i-Base graphic. The main text in red and dark blue, on a light blue blue background, reads: CROI 2025. Ensitrelvir. A COVID-19 treatment that can also prevent transmission? Below, in white on a burnt orange background, text reads, San Francisco, California. 9th to 12th March. On top of this is a faint image of the Golden Gate Bridge. In the top left corner is a URL: I hyphen base dot info. In the top right corner is a box made of blue, yellow and red blocks. White text on it reads, HTB news. 2025.

#COVID treatment used in #Japan can also prevent transmission:

i-base.info/htb/50627

People using #ensitrelvir had a much lower chance of catching #COVID19 from people they lived with.

#CROI2025 #CROI #ProteaseInhibitor #Medsky #HIVsky

#ensitrelvir is approved in 🇯🇵 as #COVID19 Tx. It reduces 🏥 for #COVID19 among people at the highest risk of complications; for the less vulnerable, it cuts down on the number of those sick with sx. @fda.gov is considering #ensitrelvir for fast-track approval as a way to prevent #COVID

Inforgraph

#Medsky🧪#IDSky #publichealth @CDCgov Increasing use of #ensitrelvir worldwide will likely increase the frequency of mutations in #SARSCoV2 causing ensitrelvir resistance.

Efficacy and Safety of 5-Day Oral Ensitrelvir for Mild to Moderate COVID-19 This randomized clinical trial assesses whether ensitrelvir reduces time to resolution of 5 common COVID-19 symptoms among patients with mild to moderate diseas

MedSky🧪#IDSky #Clinicalreport @JAMA_current Treatment with #ensitrelvir, an oral SARS-CoV-2 3C-like protease inhibitor developed in 🇯🇵 , shortened #COVID19 symptoms in people who received these #Antiviral within 3 days of symptom onset, researchers reported.

jamanetwork.com/journals/jam...