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This study explores the bidirectional associations between seborrheic dermatitis (SD) and epithelial barrier disease (EBDs) in a cohort of 5,083,689 individuals in a US administrative claims database. Positive bidirectional associations were found between SD and many EBDs of the skin, respiratory, gastrointestinal, and ocular surfaces. The results support the Epithelial Barrier Theory as a shared driver of EBD pathogenesis at both local and non-local epithelial barriers.

This study explores the bidirectional associations between seborrheic dermatitis (SD) and epithelial barrier disease (EBDs) in a cohort of 5,083,689 individuals in a US administrative claims database. Positive bidirectional associations were found between SD and many EBDs of the skin, respiratory, gastrointestinal, and ocular surfaces. The results support the Epithelial Barrier Theory as a shared driver of EBD pathogenesis at both local and non-local epithelial barriers.

Open access: Bidirectional Associations Between Seborrheic Dermatitis and #EpithelialBarrier Diseases: A Retrospective Cohort Study. Corresponding author: Sabrina Meng

👉 doi.org/10.1111/all.70112

#Allergy_journal
Read more articles 👉 journalallergy.com/barrier-and-microbiota

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🌍 Environmental exposures can disrupt skin & mucosal barriers—triggering disease.
Learn more about the epithelial barrier theory: febs.onlinelibrary.wiley.com/doi/10.1002/...
#Immunology #EpithelialBarrier #EnvironmentalHealth

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I’m a postdoctoral researcher in #immunology @ the University of Newcastle 🇦🇺. My work focuses on the small intestinal immune dysfunction in #gut conditions including #IBS, #DGBIs and #foodintolerances.

#academicsky #scisky #HiSkySci

#eosinophils #tcells #epithelialbarrier

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Evidence for lung barrier regeneration by differentiation prior to binucleated and stem cell divisio... Lung alveoli are lined by an exquisitely thin monolayer of cells adapted for gas exchange. Guild et al. elucidate a specialized regenerative program by which th

More evidence for #binucleated #polyploid AT2 cells in the lung with implications for #epithelialbarrier repair!

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