Advanced Lung Function Measurement In A Novel HIV/TB Co-infection in Mouse Models Tuberculosis and Human Immunodeficiency Virus are major global health threats. Their interaction worsens disease severity, as HIV reduces CD4+ T cells, making individuals more vulnerable to TB.

This blog discusses a study by Bohorquez et al. (2024) who developed a humanized NSG-SGM3 mouse model to advance HIV/TB co-infection studies, a model that has been lacking in co-infection research. Full blog: hubs.ly/Q03tNQGM0

#flexiVent #flexiVentLungFunction #TB #Tuberculosis #HIV

Depression of CaV1.2 activation and expression in mast cells ameliorates allergic inflammation diseases Allergic inflammation is closely related to the activation of mast cells (MCs), which is regulated by its intracellular Ca2+ level, but the intake and…

A new study published in the Journal of Pharmaceutical Analysis explores the important role of calcium channel subunit CaV1.2 in mast cell activation and allergic inflammation
Read the full study here: hubs.ly/Q02Zpfmp0

#flexiVentLungFunction #AllergyResearch #CaV1.2 #Pharmacology #DrugDevelopment